Schreiber SL - Search Results

1

Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.

Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MAS, Scadden DT, Schreiber SL, Ebert BL, Golub TR. Hartwell KA, et al. Among authors: schreiber sl. Nat Chem Biol. 2013 Dec;9(12):840-848. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27. Nat Chem Biol. 2013. PMID: 24161946 Free PMC article.

2

A miniaturized arrayed assay format for detecting small molecule-protein interactions in cells.

You AJ, Jackman RJ, Whitesides GM, Schreiber SL. You AJ, et al. Among authors: schreiber sl. Chem Biol. 1997 Dec;4(12):969-75. doi: 10.1016/s1074-5521(97)90305-7. Chem Biol. 1997. PMID: 9427662

3

High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications.

Stockwell BR, Haggarty SJ, Schreiber SL. Stockwell BR, et al. Among authors: schreiber sl. Chem Biol. 1999 Feb;6(2):71-83. doi: 10.1016/S1074-5521(99)80004-0. Chem Biol. 1999. PMID: 10021420

4

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins.

Hardwick JS, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL. Hardwick JS, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14866-70. doi: 10.1073/pnas.96.26.14866. Proc Natl Acad Sci U S A. 1999. PMID: 10611304 Free PMC article.

5

Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins.

Shamji AF, Kuruvilla FG, Schreiber SL. Shamji AF, et al. Among authors: schreiber sl. Curr Biol. 2000 Dec 14-28;10(24):1574-81. doi: 10.1016/s0960-9822(00)00866-6. Curr Biol. 2000. PMID: 11137008 Free article.

6

Exploiting site-site interactions on solid support to generate dimeric molecules.

Blackwell HE, Clemons PA, Schreiber SL. Blackwell HE, et al. Among authors: schreiber sl. Org Lett. 2001 Apr 19;3(8):1185-8. doi: 10.1021/ol015647i. Org Lett. 2001. PMID: 11348190

7

Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors.

Kuruvilla FG, Shamji AF, Schreiber SL. Kuruvilla FG, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7283-8. doi: 10.1073/pnas.121186898. Proc Natl Acad Sci U S A. 2001. PMID: 11416207 Free PMC article.

8

A one-bead, one-stock solution approach to chemical genetics: part 2.

Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397

9

Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors.

Clemons PA, Gladstone BG, Seth A, Chao ED, Foley MA, Schreiber SL. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2002 Jan;9(1):49-61. doi: 10.1016/s1074-5521(02)00085-6. Chem Biol. 2002. PMID: 11841938

10

Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays.

Kuruvilla FG, Shamji AF, Sternson SM, Hergenrother PJ, Schreiber SL. Kuruvilla FG, et al. Among authors: schreiber sl. Nature. 2002 Apr 11;416(6881):653-7. doi: 10.1038/416653a. Nature. 2002. PMID: 11948353

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