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Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.
Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MAS, Scadden DT, Schreiber SL, Ebert BL, Golub TR. Hartwell KA, et al. Among authors: scadden dt. Nat Chem Biol. 2013 Dec;9(12):840-848. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27. Nat Chem Biol. 2013. PMID: 24161946 Free PMC article.
Efficient generation of human T cells from a tissue-engineered thymic organoid.
Poznansky MC, Evans RH, Foxall RB, Olszak IT, Piascik AH, Hartman KE, Brander C, Meyer TH, Pykett MJ, Chabner KT, Kalams SA, Rosenzweig M, Scadden DT. Poznansky MC, et al. Among authors: scadden dt. Nat Biotechnol. 2000 Jul;18(7):729-34. doi: 10.1038/77288. Nat Biotechnol. 2000. PMID: 10888839
Osteoblastic cells regulate the haematopoietic stem cell niche.
Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P, Bringhurst FR, Milner LA, Kronenberg HM, Scadden DT. Calvi LM, et al. Among authors: scadden dt. Nature. 2003 Oct 23;425(6960):841-6. doi: 10.1038/nature02040. Nature. 2003. PMID: 14574413
Regulation of hematopoietic stem cell growth.
Attar EC, Scadden DT. Attar EC, et al. Among authors: scadden dt. Leukemia. 2004 Nov;18(11):1760-8. doi: 10.1038/sj.leu.2403515. Leukemia. 2004. PMID: 15457182 Review.
Nervous activity in a stem cell niche.
Larsson J, Scadden D. Larsson J, et al. Cell. 2006 Jan 27;124(2):253-5. doi: 10.1016/j.cell.2006.01.006. Cell. 2006. PMID: 16439198 Free article. Review.
The hematopoietic stem cell in its place.
Adams GB, Scadden DT. Adams GB, et al. Among authors: scadden dt. Nat Immunol. 2006 Apr;7(4):333-7. doi: 10.1038/ni1331. Nat Immunol. 2006. PMID: 16550195 Review.
398 results