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Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.
Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MAS, Scadden DT, Schreiber SL, Ebert BL, Golub TR. Hartwell KA, et al. Among authors: carpenter ae. Nat Chem Biol. 2013 Dec;9(12):840-848. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27. Nat Chem Biol. 2013. PMID: 24161946 Free PMC article.
The Spemann organizer gene, Goosecoid, promotes tumor metastasis.
Hartwell KA, Muir B, Reinhardt F, Carpenter AE, Sgroi DC, Weinberg RA. Hartwell KA, et al. Among authors: carpenter ae. Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):18969-74. doi: 10.1073/pnas.0608636103. Epub 2006 Dec 1. Proc Natl Acad Sci U S A. 2006. PMID: 17142318 Free PMC article.
Image-based chemical screening.
Carpenter AE. Carpenter AE. Nat Chem Biol. 2007 Aug;3(8):461-5. doi: 10.1038/nchembio.2007.15. Nat Chem Biol. 2007. PMID: 17637778 Review.
Abnormalities in mitochondrial structure in cells from patients with bipolar disorder.
Cataldo AM, McPhie DL, Lange NT, Punzell S, Elmiligy S, Ye NZ, Froimowitz MP, Hassinger LC, Menesale EB, Sargent LW, Logan DJ, Carpenter AE, Cohen BM. Cataldo AM, et al. Among authors: carpenter ae. Am J Pathol. 2010 Aug;177(2):575-85. doi: 10.2353/ajpath.2010.081068. Epub 2010 Jun 21. Am J Pathol. 2010. PMID: 20566748 Free PMC article.
Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice.
Elkabets M, Gifford AM, Scheel C, Nilsson B, Reinhardt F, Bray MA, Carpenter AE, Jirström K, Magnusson K, Ebert BL, Pontén F, Weinberg RA, McAllister SS. Elkabets M, et al. Among authors: carpenter ae. J Clin Invest. 2011 Feb;121(2):784-99. doi: 10.1172/JCI43757. Epub 2011 Jan 25. J Clin Invest. 2011. PMID: 21266779 Free PMC article.
201 results