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Indoleamine-2,3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans.
Stapelberg M, Zobalova R, Nguyen MN, Walker T, Stantic M, Goodwin J, Pasdar EA, Thai T, Prokopova K, Yan B, Hall S, de Pennington N, Thomas SR, Grant G, Stursa J, Bajzikova M, Meedeniya AC, Truksa J, Ralph SJ, Ansorge O, Dong LF, Neuzil J. Stapelberg M, et al. Among authors: ralph sj. Free Radic Biol Med. 2014 Feb;67:41-50. doi: 10.1016/j.freeradbiomed.2013.10.003. Epub 2013 Oct 18. Free Radic Biol Med. 2014. PMID: 24145120
Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy.
Dong LF, Jameson VJ, Tilly D, Prochazka L, Rohlena J, Valis K, Truksa J, Zobalova R, Mahdavian E, Kluckova K, Stantic M, Stursa J, Freeman R, Witting PK, Norberg E, Goodwin J, Salvatore BA, Novotna J, Turanek J, Ledvina M, Hozak P, Zhivotovsky B, Coster MJ, Ralph SJ, Smith RA, Neuzil J. Dong LF, et al. Among authors: ralph sj. Free Radic Biol Med. 2011 Jun 1;50(11):1546-55. doi: 10.1016/j.freeradbiomed.2011.02.032. Epub 2011 Mar 12. Free Radic Biol Med. 2011. PMID: 21402148
Tumour-initiating cells vs. cancer 'stem' cells and CD133: what's in the name?
Neuzil J, Stantic M, Zobalova R, Chladova J, Wang X, Prochazka L, Dong L, Andera L, Ralph SJ. Neuzil J, et al. Among authors: ralph sj. Biochem Biophys Res Commun. 2007 Apr 20;355(4):855-9. doi: 10.1016/j.bbrc.2007.01.159. Epub 2007 Feb 6. Biochem Biophys Res Commun. 2007. PMID: 17307142 Review.
Mitochondria as targets for cancer therapy.
Ralph SJ, Neuzil J. Ralph SJ, et al. Mol Nutr Food Res. 2009 Jan;53(1):9-28. doi: 10.1002/mnfr.200800044. Mol Nutr Food Res. 2009. PMID: 19123183 Review.
Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II.
Dong LF, Freeman R, Liu J, Zobalova R, Marin-Hernandez A, Stantic M, Rohlena J, Valis K, Rodriguez-Enriquez S, Butcher B, Goodwin J, Brunk UT, Witting PK, Moreno-Sanchez R, Scheffler IE, Ralph SJ, Neuzil J. Dong LF, et al. Among authors: ralph sj. Clin Cancer Res. 2009 Mar 1;15(5):1593-600. doi: 10.1158/1078-0432.CCR-08-2439. Epub 2009 Feb 17. Clin Cancer Res. 2009. PMID: 19223492
92 results