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Indoleamine-2,3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans.
Stapelberg M, Zobalova R, Nguyen MN, Walker T, Stantic M, Goodwin J, Pasdar EA, Thai T, Prokopova K, Yan B, Hall S, de Pennington N, Thomas SR, Grant G, Stursa J, Bajzikova M, Meedeniya AC, Truksa J, Ralph SJ, Ansorge O, Dong LF, Neuzil J. Stapelberg M, et al. Among authors: goodwin j. Free Radic Biol Med. 2014 Feb;67:41-50. doi: 10.1016/j.freeradbiomed.2013.10.003. Epub 2013 Oct 18. Free Radic Biol Med. 2014. PMID: 24145120
Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy.
Dong LF, Jameson VJ, Tilly D, Prochazka L, Rohlena J, Valis K, Truksa J, Zobalova R, Mahdavian E, Kluckova K, Stantic M, Stursa J, Freeman R, Witting PK, Norberg E, Goodwin J, Salvatore BA, Novotna J, Turanek J, Ledvina M, Hozak P, Zhivotovsky B, Coster MJ, Ralph SJ, Smith RA, Neuzil J. Dong LF, et al. Among authors: goodwin j. Free Radic Biol Med. 2011 Jun 1;50(11):1546-55. doi: 10.1016/j.freeradbiomed.2011.02.032. Epub 2011 Mar 12. Free Radic Biol Med. 2011. PMID: 21402148
Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents.
Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J. Pasdar EA, et al. Among authors: goodwin j. PLoS One. 2015 May 1;10(5):e0119549. doi: 10.1371/journal.pone.0119549. eCollection 2015. PLoS One. 2015. PMID: 25932953 Free PMC article.
Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II.
Dong LF, Freeman R, Liu J, Zobalova R, Marin-Hernandez A, Stantic M, Rohlena J, Valis K, Rodriguez-Enriquez S, Butcher B, Goodwin J, Brunk UT, Witting PK, Moreno-Sanchez R, Scheffler IE, Ralph SJ, Neuzil J. Dong LF, et al. Among authors: goodwin j. Clin Cancer Res. 2009 Mar 1;15(5):1593-600. doi: 10.1158/1078-0432.CCR-08-2439. Epub 2009 Feb 17. Clin Cancer Res. 2009. PMID: 19223492
Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing.
Rohlena J, Dong LF, Kluckova K, Zobalova R, Goodwin J, Tilly D, Stursa J, Pecinova A, Philimonenko A, Hozak P, Banerjee J, Ledvina M, Sen CK, Houstek J, Coster MJ, Neuzil J. Rohlena J, et al. Among authors: goodwin j. Antioxid Redox Signal. 2011 Dec 15;15(12):2923-35. doi: 10.1089/ars.2011.4192. Antioxid Redox Signal. 2011. PMID: 21902599 Free PMC article.
Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis.
Truksa J, Dong LF, Rohlena J, Stursa J, Vondrusova M, Goodwin J, Nguyen M, Kluckova K, Rychtarcikova Z, Lettlova S, Spacilova J, Stapelberg M, Zoratti M, Neuzil J. Truksa J, et al. Among authors: goodwin j. Antioxid Redox Signal. 2015 Apr 10;22(11):883-900. doi: 10.1089/ars.2013.5594. Epub 2015 Feb 25. Antioxid Redox Signal. 2015. PMID: 25578105
Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer.
Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alizadeh Pesdar E, Yan B, Nguyen MN, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong LF, Neuzil J. Rohlenova K, et al. Among authors: goodwin j. Antioxid Redox Signal. 2017 Jan 10;26(2):84-103. doi: 10.1089/ars.2016.6677. Epub 2016 Aug 22. Antioxid Redox Signal. 2017. PMID: 27392540 Free PMC article.
Corrigendum to: "Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy" [Free Radic Biol Med. 50 (2011) 1546-1555].
Dong LF, Jameson VJA, Tilly D, Prochazka L, Rohlena J, Valis K, Truksa J, Zobalova R, Mahdavian E, Kluckova K, Stantic M, Stursa J, Freeman R, Witting PK, Norberg E, Goodwin J, Salvatore BA, Novotna J, Turanek J, Ledvina M, Hozak P, Zhivotovsky B, Coster MJ, Ralph SJ, Smith RAJ, Neuzil J. Dong LF, et al. Among authors: goodwin j. Free Radic Biol Med. 2013 Dec;65:895-896. doi: 10.1016/j.freeradbiomed.2013.08.164. Epub 2013 Aug 29. Free Radic Biol Med. 2013. PMID: 30184722 No abstract available.
1,760 results