Hogg P - Search Results

1

A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours.

Horsley L, Cummings J, Middleton M, Ward T, Backen A, Clamp A, Dawson M, Farmer H, Fisher N, Halbert G, Halford S, Harris A, Hasan J, Hogg P, Kumaran G, Little R, Parker GJ, Potter P, Saunders M, Roberts C, Shaw D, Smith N, Smythe J, Taylor A, Turner H, Watson Y, Dive C, Jayson GC; Cancer Research UK Drug Development Office Phase I clinical trial. Horsley L, et al. Among authors: hogg p. Cancer Chemother Pharmacol. 2013 Dec;72(6):1343-52. doi: 10.1007/s00280-013-2320-9. Epub 2013 Oct 20. Cancer Chemother Pharmacol. 2013. PMID: 24141375 Clinical Trial.

2

Pharmaceutical development of the novel arsenical based cancer therapeutic GSAO for Phase I clinical trial.

Elliott MA, Ford SJ, Prasad E, Dick LJ, Farmer H, Hogg PJ, Halbert GW. Elliott MA, et al. Among authors: hogg pj. Int J Pharm. 2012 Apr 15;426(1-2):67-75. doi: 10.1016/j.ijpharm.2012.01.024. Epub 2012 Jan 21. Int J Pharm. 2012. PMID: 22286018 Clinical Trial.

3

Molecular profiling of signalling proteins for effects induced by the anti-cancer compound GSAO with 400 antibodies.

Cadd VA, Hogg PJ, Harris AL, Feller SM. Cadd VA, et al. BMC Cancer. 2006 Jun 9;6:155. doi: 10.1186/1471-2407-6-155. BMC Cancer. 2006. PMID: 16764713 Free PMC article.

4

Elimination of the antimicrobial action of the organoarsenical cancer therapeutic, 4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid, before finished product sterility testing.

Dick LJ, Gray A, Ram A, Hume A, Parris C, Hogg PJ, Elliott MA, Ford SJ, Halbert GW. Dick LJ, et al. J Pharm Pharmacol. 2013 Nov;65(11):1664-9. doi: 10.1111/jphp.12143. Epub 2013 Sep 18. J Pharm Pharmacol. 2013. PMID: 24102542 Free PMC article.

5

A phase 1 trial of 4-(N-(S-penicillaminylacetyl)amino)-phenylarsonous acid (PENAO) in patients with advanced solid tumours.

Sarkar S, Tran B, Horvath L, Lam M, Savas P, Grimison P, Whittle JR, Kuo JC, Signal N, Edmonds D, Hogg P, Rischin D, Desai J, Hamilton A. Sarkar S, et al. Among authors: hogg p. Cancer Chemother Pharmacol. 2021 May;87(5):613-620. doi: 10.1007/s00280-020-04225-7. Epub 2021 Jan 26. Cancer Chemother Pharmacol. 2021. PMID: 33496801 Clinical Trial.

6

Para to ortho repositioning of the arsenical moiety of the angiogenesis inhibitor 4-(N-(S-glutathionylacetyl)amino)phenylarsenoxide results in a markedly increased cellular accumulation and antiproliferative activity.

Dilda PJ, Decollogne S, Rossiter-Thornton M, Hogg PJ. Dilda PJ, et al. Cancer Res. 2005 Dec 15;65(24):11729-34. doi: 10.1158/0008-5472.CAN-05-2797. Cancer Res. 2005. PMID: 16357185

7

Metabolism of the tumor angiogenesis inhibitor 4-(N-(S-Glutathionylacetyl)amino)phenylarsonous acid.

Dilda PJ, Ramsay EE, Corti A, Pompella A, Hogg PJ. Dilda PJ, et al. J Biol Chem. 2008 Dec 19;283(51):35428-34. doi: 10.1074/jbc.M804470200. Epub 2008 Aug 23. J Biol Chem. 2008. PMID: 18723877 Free article.

8

The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase.

Park D, Chiu J, Perrone GG, Dilda PJ, Hogg PJ. Park D, et al. Cancer Cell Int. 2012 Mar 26;12(1):11. doi: 10.1186/1475-2867-12-11. Cancer Cell Int. 2012. PMID: 22448968 Free PMC article.

9

Arsenical-based cancer drugs.

Dilda PJ, Hogg PJ. Dilda PJ, et al. Cancer Treat Rev. 2007 Oct;33(6):542-64. doi: 10.1016/j.ctrv.2007.05.001. Epub 2007 Jul 10. Cancer Treat Rev. 2007. PMID: 17624680 Review.

10

A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells.

Don AS, Kisker O, Dilda P, Donoghue N, Zhao X, Decollogne S, Creighton B, Flynn E, Folkman J, Hogg PJ. Don AS, et al. Among authors: hogg pj. Cancer Cell. 2003 May;3(5):497-509. doi: 10.1016/s1535-6108(03)00109-0. Cancer Cell. 2003. PMID: 12781367 Free article.

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