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Page 1
Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3'S)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)phenyl] amide as histamine H(3) receptor antagonist for the treatment of depression.
Gao Z, Hurst WJ, Czechtizky W, Hall D, Moindrot N, Nagorny R, Pichat P, Stefany D, Hendrix JA, George PG. Gao Z, et al. Among authors: pichat p. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6269-73. doi: 10.1016/j.bmcl.2013.09.081. Epub 2013 Oct 3. Bioorg Med Chem Lett. 2013. PMID: 24139584
Synthesis and biological evaluation of analogues of M6G.
Trécant C, Dlubala A, George P, Pichat P, Ripoche I, Troin Y. Trécant C, et al. Among authors: pichat p. Eur J Med Chem. 2011 Sep;46(9):4035-41. doi: 10.1016/j.ejmech.2011.05.076. Epub 2011 Jun 12. Eur J Med Chem. 2011. PMID: 21689868
SAR110894, a potent histamine H₃-receptor antagonist, displays procognitive effects in rodents.
Griebel G, Pichat P, Pruniaux MP, Beeské S, Lopez-Grancha M, Genet E, Terranova JP, Castro A, Sánchez JA, Black M, Varty GB, Weiner I, Arad M, Barak S, De Levie A, Guillot E. Griebel G, et al. Among authors: pichat p. Pharmacol Biochem Behav. 2012 Aug;102(2):203-14. doi: 10.1016/j.pbb.2012.04.004. Epub 2012 Apr 21. Pharmacol Biochem Behav. 2012. PMID: 22542742
Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia.
Boulay D, Pichat P, Dargazanli G, Estenne-Bouhtou G, Terranova JP, Rogacki N, Stemmelin J, Coste A, Lanneau C, Desvignes C, Cohen C, Alonso R, Vigé X, Biton B, Steinberg R, Sevrin M, Oury-Donat F, George P, Bergis O, Griebel G, Avenet P, Scatton B. Boulay D, et al. Among authors: pichat p. Pharmacol Biochem Behav. 2008 Nov;91(1):47-58. doi: 10.1016/j.pbb.2008.06.009. Epub 2008 Jun 24. Pharmacol Biochem Behav. 2008. PMID: 18621075
Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.
Griebel G, Pichat P, Beeské S, Leroy T, Redon N, Jacquet A, Françon D, Bert L, Even L, Lopez-Grancha M, Tolstykh T, Sun F, Yu Q, Brittain S, Arlt H, He T, Zhang B, Wiederschain D, Bertrand T, Houtmann J, Rak A, Vallée F, Michot N, Augé F, Menet V, Bergis OE, George P, Avenet P, Mikol V, Didier M, Escoubet J. Griebel G, et al. Among authors: pichat p. Sci Rep. 2015 Jan 6;5:7642. doi: 10.1038/srep07642. Sci Rep. 2015. PMID: 25560837 Free PMC article.
Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders.
Stemmelin J, Cohen C, Terranova JP, Lopez-Grancha M, Pichat P, Bergis O, Decobert M, Santucci V, Françon D, Alonso R, Stahl SM, Keane P, Avenet P, Scatton B, le Fur G, Griebel G. Stemmelin J, et al. Among authors: pichat p. Neuropsychopharmacology. 2008 Feb;33(3):574-87. doi: 10.1038/sj.npp.1301424. Epub 2007 Apr 25. Neuropsychopharmacology. 2008. PMID: 17460614
SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia.
Pichat P, Bergis OE, Terranova JP, Urani A, Duarte C, Santucci V, Gueudet C, Voltz C, Steinberg R, Stemmelin J, Oury-Donat F, Avenet P, Griebel G, Scatton B. Pichat P, et al. Neuropsychopharmacology. 2007 Jan;32(1):17-34. doi: 10.1038/sj.npp.1301188. Epub 2006 Aug 23. Neuropsychopharmacology. 2007. PMID: 16936709
Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat.
Black MD, Varty GB, Arad M, Barak S, De Levie A, Boulay D, Pichat P, Griebel G, Weiner I. Black MD, et al. Among authors: pichat p. Psychopharmacology (Berl). 2009 Jan;202(1-3):385-96. doi: 10.1007/s00213-008-1289-2. Epub 2008 Aug 16. Psychopharmacology (Berl). 2009. PMID: 18709358
51 results