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Genomically recoded organisms expand biological functions.
Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, Isaacs FJ. Lajoie MJ, et al. Among authors: jacobson jm. Science. 2013 Oct 18;342(6156):357-60. doi: 10.1126/science.1241459. Science. 2013. PMID: 24136966 Free PMC article.
Protein-mediated error correction for de novo DNA synthesis.
Carr PA, Park JS, Lee YJ, Yu T, Zhang S, Jacobson JM. Carr PA, et al. Among authors: jacobson jm. Nucleic Acids Res. 2004 Nov 23;32(20):e162. doi: 10.1093/nar/gnh160. Nucleic Acids Res. 2004. PMID: 15561997 Free PMC article.
Parallel gene synthesis in a microfluidic device.
Kong DS, Carr PA, Chen L, Zhang S, Jacobson JM. Kong DS, et al. Among authors: jacobson jm. Nucleic Acids Res. 2007;35(8):e61. doi: 10.1093/nar/gkm121. Epub 2007 Apr 2. Nucleic Acids Res. 2007. PMID: 17405768 Free PMC article.
Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.
Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB, Emig CJ, Bang D, Hwang SJ, Jewett MC, Jacobson JM, Church GM. Isaacs FJ, et al. Among authors: jacobson jm. Science. 2011 Jul 15;333(6040):348-53. doi: 10.1126/science.1205822. Science. 2011. PMID: 21764749 Free PMC article.
PAM-flexible genome editing with an engineered chimeric Cas9.
Zhao L, Koseki SRT, Silverstein RA, Amrani N, Peng C, Kramme C, Savic N, Pacesa M, Rodríguez TC, Stan T, Tysinger E, Hong L, Yudistyra V, Ponnapati MR, Jacobson JM, Church GM, Jakimo N, Truant R, Jinek M, Kleinstiver BP, Sontheimer EJ, Chatterjee P. Zhao L, et al. Among authors: jacobson jm. Nat Commun. 2023 Oct 4;14(1):6175. doi: 10.1038/s41467-023-41829-y. Nat Commun. 2023. PMID: 37794046 Free PMC article.
How to grow (almost) anything: a hybrid distance learning model for global laboratory-based synthetic biology education.
Perry E, Weber J, Pataranutaporn P, Volf V, Gonzalez LM, Nejad S, Angleton C, Chen JE, Gabo A, Jammalamadaka MSS, Kuru E, Fortuna P, Rico A, Sulich K, Wawrzyniak D, Jacobson J, Church G, Kong D. Perry E, et al. Nat Biotechnol. 2022 Dec;40(12):1874-1879. doi: 10.1038/s41587-022-01601-x. Nat Biotechnol. 2022. PMID: 36510008 No abstract available.
Minimal PAM specificity of a highly similar SpCas9 ortholog.
Chatterjee P, Jakimo N, Jacobson JM. Chatterjee P, et al. Among authors: jacobson jm. Sci Adv. 2018 Oct 24;4(10):eaau0766. doi: 10.1126/sciadv.aau0766. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30397647 Free PMC article.
258 results