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Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index.
Sci Transl Med. 2013 Oct 16;5(207):207ra144. doi: 10.1126/scitranslmed.3006682.
Sci Transl Med. 2013.
PMID: 24132639
In vivo imaging of protease activity by Probody therapeutic activation.
Wong KR, Menendez E, Craik CS, Kavanaugh WM, Vasiljeva O.
Wong KR, et al.
Biochimie. 2016 Mar;122:62-7. doi: 10.1016/j.biochi.2015.11.003. Epub 2015 Nov 4.
Biochimie. 2016.
PMID: 26546838
Free PMC article.
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Monitoring protease activity in biological tissues using antibody prodrugs as sensing probes.
Vasiljeva O, Menendez E, Nguyen M, Craik CS, Michael Kavanaugh W.
Vasiljeva O, et al.
Sci Rep. 2020 Apr 3;10(1):5894. doi: 10.1038/s41598-020-62339-7.
Sci Rep. 2020.
PMID: 32246002
Free PMC article.
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