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Approaches to the synthesis of a novel, anti-HIV active integrase inhibitor.
Org Biomol Chem. 2013 Dec 7;11(45):7852-8. doi: 10.1039/c3ob41728j. Epub 2013 Oct 7.
Org Biomol Chem. 2013.
PMID: 24100441
Free PMC article.
Discovery of a Potent HIV Integrase Inhibitor that Leads to a Prodrug with Significant anti-HIV Activity.
Seo BI, Uchil VR, Okello M, Mishra S, Ma XH, Nishonov M, Shu Q, Chi G, Nair V.
Seo BI, et al. Among authors: nishonov m.
ACS Med Chem Lett. 2011 Oct 5;2(12):877-881. doi: 10.1021/ml2001246.
ACS Med Chem Lett. 2011.
PMID: 22328963
Free PMC article.
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A novel anti-HIV active integrase inhibitor with a favorable in vitro cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase metabolism profile.
Okello MO, Mishra S, Nishonov M, Mankowski MK, Russell JD, Wei J, Hogan PA, Ptak RG, Nair V.
Okello MO, et al. Among authors: nishonov m.
Antiviral Res. 2013 Jun;98(3):365-72. doi: 10.1016/j.antiviral.2013.04.005. Epub 2013 Apr 18.
Antiviral Res. 2013.
PMID: 23602851
Free PMC article.
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Notable difference in anti-HIV activity of integrase inhibitors as a consequence of geometric and enantiomeric configurations.
Okello M, Mishra S, Nishonov M, Nair V.
Okello M, et al. Among authors: nishonov m.
Bioorg Med Chem Lett. 2013 Jul 15;23(14):4112-6. doi: 10.1016/j.bmcl.2013.05.050. Epub 2013 May 23.
Bioorg Med Chem Lett. 2013.
PMID: 23746474
Free PMC article.
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