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A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
De Genst E, Chan PH, Pardon E, Hsu SD, Kumita JR, Christodoulou J, Menzer L, Chirgadze DY, Robinson CV, Muyldermans S, Matagne A, Wyns L, Dobson CM, Dumoulin M. De Genst E, et al. Among authors: dumoulin m. J Phys Chem B. 2013 Oct 24;117(42):13245-13258. doi: 10.1021/jp403425z. Epub 2013 Sep 24. J Phys Chem B. 2013. PMID: 23919586 Free PMC article.
Combinatorial Design of a Nanobody that Specifically Targets Structured RNAs.
Cawez F, Duray E, Hu Y, Vandenameele J, Romão E, Vincke C, Dumoulin M, Galleni M, Muyldermans S, Vandevenne M. Cawez F, et al. Among authors: dumoulin m. J Mol Biol. 2018 May 25;430(11):1652-1670. doi: 10.1016/j.jmb.2018.03.032. Epub 2018 Apr 11. J Mol Biol. 2018. PMID: 29654796 Free article.
Single-domain antibody fragments with high conformational stability.
Dumoulin M, Conrath K, Van Meirhaeghe A, Meersman F, Heremans K, Frenken LG, Muyldermans S, Wyns L, Matagne A. Dumoulin M, et al. Protein Sci. 2002 Mar;11(3):500-15. doi: 10.1110/ps.34602. Protein Sci. 2002. PMID: 11847273 Free PMC article.
161 results