Nicoll AJ - Search Results

1

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity.

Nicoll AJ, Panico S, Freir DB, Wright D, Terry C, Risse E, Herron CE, O'Malley T, Wadsworth JD, Farrow MA, Walsh DM, Saibil HR, Collinge J. Nicoll AJ, et al. Nat Commun. 2013;4:2416. doi: 10.1038/ncomms3416. Nat Commun. 2013. PMID: 24022506 Free PMC article.

2

Preventing prion pathogenicity by targeting the cellular prion protein.

Nicoll AJ, Collinge J. Nicoll AJ, et al. Infect Disord Drug Targets. 2009 Feb;9(1):48-57. doi: 10.2174/1871526510909010048. Infect Disord Drug Targets. 2009. PMID: 19200015 Review.

3

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites.

Freir DB, Nicoll AJ, Klyubin I, Panico S, Mc Donald JM, Risse E, Asante EA, Farrow MA, Sessions RB, Saibil HR, Clarke AR, Rowan MJ, Walsh DM, Collinge J. Freir DB, et al. Among authors: nicoll aj. Nat Commun. 2011 Jun 7;2:336. doi: 10.1038/ncomms1341. Nat Commun. 2011. PMID: 21654636 Free PMC article.

4

mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo.

Hu NW, Nicoll AJ, Zhang D, Mably AJ, O'Malley T, Purro SA, Terry C, Collinge J, Walsh DM, Rowan MJ. Hu NW, et al. Among authors: nicoll aj. Nat Commun. 2014 Mar 4;5:3374. doi: 10.1038/ncomms4374. Nat Commun. 2014. PMID: 24594908 Free PMC article.

5

Peripheral administration of a humanized anti-PrP antibody blocks Alzheimer's disease Aβ synaptotoxicity.

Klyubin I, Nicoll AJ, Khalili-Shirazi A, Farmer M, Canning S, Mably A, Linehan J, Brown A, Wakeling M, Brandner S, Walsh DM, Rowan MJ, Collinge J. Klyubin I, et al. Among authors: nicoll aj. J Neurosci. 2014 Apr 30;34(18):6140-5. doi: 10.1523/JNEUROSCI.3526-13.2014. J Neurosci. 2014. PMID: 24790184 Free PMC article.

6

N-terminal domain of prion protein directs its oligomeric association.

Trevitt CR, Hosszu LL, Batchelor M, Panico S, Terry C, Nicoll AJ, Risse E, Taylor WA, Sandberg MK, Al-Doujaily H, Linehan JM, Saibil HR, Scott DJ, Collinge J, Waltho JP, Clarke AR. Trevitt CR, et al. Among authors: nicoll aj. J Biol Chem. 2014 Sep 12;289(37):25497-508. doi: 10.1074/jbc.M114.566588. Epub 2014 Jul 29. J Biol Chem. 2014. PMID: 25074940 Free PMC article.

7

Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay.

Risse E, Nicoll AJ, Taylor WA, Wright D, Badoni M, Yang X, Farrow MA, Collinge J. Risse E, et al. Among authors: nicoll aj. J Biol Chem. 2015 Jul 3;290(27):17020-8. doi: 10.1074/jbc.M115.637124. Epub 2015 May 20. J Biol Chem. 2015. PMID: 25995455 Free PMC article.

8

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy.

Jaunmuktane Z, Mead S, Ellis M, Wadsworth JD, Nicoll AJ, Kenny J, Launchbury F, Linehan J, Richard-Loendt A, Walker AS, Rudge P, Collinge J, Brandner S. Jaunmuktane Z, et al. Among authors: nicoll aj. Nature. 2015 Sep 10;525(7568):247-50. doi: 10.1038/nature15369. Nature. 2015. PMID: 26354483

9

Soluble Aβ aggregates can inhibit prion propagation.

Sarell CJ, Quarterman E, Yip DC, Terry C, Nicoll AJ, Wadsworth JDF, Farrow MA, Walsh DM, Collinge J. Sarell CJ, et al. Among authors: nicoll aj. Open Biol. 2017 Nov;7(11):170158. doi: 10.1098/rsob.170158. Open Biol. 2017. PMID: 29142106 Free PMC article.

10

Prion Protein as a Toxic Acceptor of Amyloid-β Oligomers.

Purro SA, Nicoll AJ, Collinge J. Purro SA, et al. Among authors: nicoll aj. Biol Psychiatry. 2018 Feb 15;83(4):358-368. doi: 10.1016/j.biopsych.2017.11.020. Epub 2017 Nov 21. Biol Psychiatry. 2018. PMID: 29331212 Review.

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