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The antihelmintic drug pyrvinium pamoate targets aggressive breast cancer.
Xu W, Lacerda L, Debeb BG, Atkinson RL, Solley TN, Li L, Orton D, McMurray JS, Hang BI, Lee E, Klopp AH, Ueno NT, Reuben JM, Krishnamurthy S, Woodward WA. Xu W, et al. Among authors: hang bi. PLoS One. 2013 Aug 27;8(8):e71508. doi: 10.1371/journal.pone.0071508. eCollection 2013. PLoS One. 2013. PMID: 24013655 Free PMC article.
Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, Robbins DJ. Li B, et al. Cancer Res. 2014 Sep 1;74(17):4811-21. doi: 10.1158/0008-5472.CAN-14-0317. Epub 2014 Jul 3. Cancer Res. 2014. PMID: 24994715 Free PMC article.
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.
Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM 3rd, Lee E. Thorne CA, et al. Among authors: hang bi. Nat Chem Biol. 2010 Nov;6(11):829-36. doi: 10.1038/nchembio.453. Epub 2010 Oct 3. Nat Chem Biol. 2010. PMID: 20890287 Free PMC article.
Corrigendum to "The active phthalate metabolite, DHEP, induces proliferation and metastasis of prostate cancer cells via upregulation of β-catenin and downregulation of KLF7" [Bioorganic Chem., 141 (2023) 106864].
Li H, Li J, Ma Y, Wang Z, Peng Z, Xu H, Bi H, Althaf Hussain S, Li Z. Li H, et al. Among authors: bi h. Bioorg Chem. 2024 Feb;143:106956. doi: 10.1016/j.bioorg.2023.106956. Epub 2023 Nov 30. Bioorg Chem. 2024. PMID: 38036376 No abstract available.
13 results