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Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation.
Holly SP, Chang JW, Li W, Niessen S, Phillips RM, Piatt R, Black JL, Smith MC, Boulaftali Y, Weyrich AS, Bergmeier W, Cravatt BF, Parise LV. Holly SP, et al. Among authors: weyrich as. Chem Biol. 2013 Sep 19;20(9):1125-34. doi: 10.1016/j.chembiol.2013.07.011. Epub 2013 Aug 29. Chem Biol. 2013. PMID: 23993462 Free PMC article.
RASA3 is a critical inhibitor of RAP1-dependent platelet activation.
Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, Mackman N, Weyrich AS, Parrott MC, Boulaftali Y, Adams MD, Peters LL, Bergmeier W. Stefanini L, et al. Among authors: weyrich as. J Clin Invest. 2015 Apr;125(4):1419-32. doi: 10.1172/JCI77993. Epub 2015 Feb 23. J Clin Invest. 2015. PMID: 25705885 Free PMC article.
Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice.
Paul DS, Casari C, Wu C, Piatt R, Pasala S, Campbell RA, Poe KO, Ghalloussi D, Lee RH, Rotty JD, Cooley BC, Machlus KR, Italiano JE Jr, Weyrich AS, Bear JE, Bergmeier W. Paul DS, et al. Among authors: weyrich as. Blood Adv. 2017 Aug 8;1(18):1398-1408. doi: 10.1182/bloodadvances.2017006973. Blood Adv. 2017. PMID: 29104956 Free PMC article.
Proteasome function is required for platelet production.
Shi DS, Smith MC, Campbell RA, Zimmerman PW, Franks ZB, Kraemer BF, Machlus KR, Ling J, Kamba P, Schwertz H, Rowley JW, Miles RR, Liu ZJ, Sola-Visner M, Italiano JE Jr, Christensen H, Kahr WH, Li DY, Weyrich AS. Shi DS, et al. Among authors: weyrich as. J Clin Invest. 2014 Sep;124(9):3757-66. doi: 10.1172/JCI75247. Epub 2014 Jul 25. J Clin Invest. 2014. PMID: 25061876 Free PMC article.
Platelet precursors display bipolar behavior.
Schwertz H, Weyrich AS. Schwertz H, et al. Among authors: weyrich as. J Cell Biol. 2010 Nov 15;191(4):699-700. doi: 10.1083/jcb.201010082. J Cell Biol. 2010. PMID: 21079242 Free PMC article.
175 results