Packham G - Search Results

1

miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance.

Zhang L, Pickard K, Jenei V, Bullock MD, Bruce A, Mitter R, Kelly G, Paraskeva C, Strefford J, Primrose J, Thomas GJ, Packham G, Mirnezami AH. Zhang L, et al. Among authors: packham g. Cancer Res. 2013 Nov 1;73(21):6435-47. doi: 10.1158/0008-5472.CAN-12-3308. Epub 2013 Aug 15. Cancer Res. 2013. PMID: 23950211 Free PMC article.

2

BAG-1 expression and function in human cancer.

Cutress RI, Townsend PA, Brimmell M, Bateman AC, Hague A, Packham G. Cutress RI, et al. Among authors: packham g. Br J Cancer. 2002 Oct 7;87(8):834-9. doi: 10.1038/sj.bjc.6600538. Br J Cancer. 2002. PMID: 12373595 Free PMC article. Review.

3

BAG-1 prevents stress-induced long-term growth inhibition in breast cancer cells via a chaperone-dependent pathway.

Townsend PA, Cutress RI, Sharp A, Brimmell M, Packham G. Townsend PA, et al. Among authors: packham g. Cancer Res. 2003 Jul 15;63(14):4150-7. Cancer Res. 2003. PMID: 12874020

4

Nuclear BAG-1 expression inhibits apoptosis in colorectal adenoma-derived epithelial cells.

Barnes JD, Arhel NJ, Lee SS, Sharp A, Al-Okail M, Packham G, Hague A, Paraskeva C, Williams AC. Barnes JD, et al. Among authors: packham g. Apoptosis. 2005 Mar;10(2):301-11. doi: 10.1007/s10495-005-0804-8. Apoptosis. 2005. PMID: 15843891

5

The role of the retinoblastoma protein (Rb) in the nuclear localization of BAG-1: implications for colorectal tumour cell survival.

Clemo NK, Arhel NJ, Barnes JD, Baker J, Moorghen M, Packham GK, Paraskeva C, Williams AC. Clemo NK, et al. Among authors: packham gk. Biochem Soc Trans. 2005 Aug;33(Pt 4):676-8. doi: 10.1042/BST0330676. Biochem Soc Trans. 2005. PMID: 16042572 Review.

6

BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-kappaB activity.

Clemo NK, Collard TJ, Southern SL, Edwards KD, Moorghen M, Packham G, Hague A, Paraskeva C, Williams AC. Clemo NK, et al. Among authors: packham g. Carcinogenesis. 2008 Apr;29(4):849-57. doi: 10.1093/carcin/bgn004. Epub 2008 Jan 19. Carcinogenesis. 2008. PMID: 18204076

7

Characterisation of the in vitro activity of the depsipeptide histone deacetylase inhibitor spiruchostatin A.

Crabb SJ, Howell M, Rogers H, Ishfaq M, Yurek-George A, Carey K, Pickering BM, East P, Mitter R, Maeda S, Johnson PW, Townsend P, Shin-ya K, Yoshida M, Ganesan A, Packham G. Crabb SJ, et al. Among authors: packham g. Biochem Pharmacol. 2008 Aug 15;76(4):463-75. doi: 10.1016/j.bcp.2008.06.004. Epub 2008 Jun 20. Biochem Pharmacol. 2008. PMID: 18611394

8

MicroRNAs: key players in carcinogenesis and novel therapeutic targets.

Mirnezami AH, Pickard K, Zhang L, Primrose JN, Packham G. Mirnezami AH, et al. Among authors: packham g. Eur J Surg Oncol. 2009 Apr;35(4):339-47. doi: 10.1016/j.ejso.2008.06.006. Epub 2008 Jul 21. Eur J Surg Oncol. 2009. PMID: 18644693 Review.

9

The desmoplastic reaction surrounding hepatic colorectal adenocarcinoma metastases aids tumor growth and survival via alphav integrin ligation.

Conti JA, Kendall TJ, Bateman A, Armstrong TA, Papa-Adams A, Xu Q, Packham G, Primrose JN, Benyon RC, Iredale JP. Conti JA, et al. Among authors: packham g. Clin Cancer Res. 2008 Oct 15;14(20):6405-13. doi: 10.1158/1078-0432.CCR-08-0816. Clin Cancer Res. 2008. PMID: 18927279 Free PMC article.

10

The BAG-1 cochaperone is a negative regulator of p73-dependent transcription.

Wang XH, O'Connor D, Brimmell M, Packham G. Wang XH, et al. Among authors: packham g. Br J Cancer. 2009 Apr 21;100(8):1347-57. doi: 10.1038/sj.bjc.6604985. Epub 2009 Mar 17. Br J Cancer. 2009. PMID: 19293798 Free PMC article.

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