Tobe K - Search Results

1

Genome-wide association study identifies three novel loci for type 2 diabetes.

Hara K, Fujita H, Johnson TA, Yamauchi T, Yasuda K, Horikoshi M, Peng C, Hu C, Ma RC, Imamura M, Iwata M, Tsunoda T, Morizono T, Shojima N, So WY, Leung TF, Kwan P, Zhang R, Wang J, Yu W, Maegawa H, Hirose H; DIAGRAM consortium; Kaku K, Ito C, Watada H, Tanaka Y, Tobe K, Kashiwagi A, Kawamori R, Jia W, Chan JC, Teo YY, Shyong TE, Kamatani N, Kubo M, Maeda S, Kadowaki T. Hara K, et al. Among authors: tobe k. Hum Mol Genet. 2014 Jan 1;23(1):239-46. doi: 10.1093/hmg/ddt399. Epub 2013 Aug 14. Hum Mol Genet. 2014. PMID: 23945395

2

Identification of a 190-kDa protein as a novel substrate for the insulin receptor kinase functionally similar to insulin receptor substrate-1.

Tobe K, Tamemoto H, Yamauchi T, Aizawa S, Yazaki Y, Kadowaki T. Tobe K, et al. J Biol Chem. 1995 Mar 17;270(11):5698-701. doi: 10.1074/jbc.270.11.5698. J Biol Chem. 1995. PMID: 7534300 Free article.

Recently, we generated mice with a targeted disruption of the insulin receptor substrate-1 (IRS-1) gene and demonstrated that they exhibited growth retardation and mild insulin resistance, suggesting the presence of IRS-1-independent pathway that partially substitutes for IRS-1 i …

Recently, we generated mice with a targeted disruption of the insulin receptor substrate-1 (IRS-1) gene and demonstrated that they exhibited …

3

Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes.

Seko Y, Tobe K, Ueki K, Kadowaki T, Yazaki Y. Seko Y, et al. Among authors: tobe k. Circ Res. 1996 Jan;78(1):82-90. doi: 10.1161/01.res.78.1.82. Circ Res. 1996. PMID: 8603510

4

Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice.

Yamauchi T, Tobe K, Tamemoto H, Ueki K, Kaburagi Y, Yamamoto-Honda R, Takahashi Y, Yoshizawa F, Aizawa S, Akanuma Y, Sonenberg N, Yazaki Y, Kadowaki T. Yamauchi T, et al. Among authors: tobe k. Mol Cell Biol. 1996 Jun;16(6):3074-84. doi: 10.1128/MCB.16.6.3074. Mol Cell Biol. 1996. PMID: 8649419 Free PMC article.

5

Insulin resistance syndrome in mice deficient in insulin receptor substrate-1.

Tamemoto H, Tobe K, Yamauchi T, Terauchi Y, Kaburagi Y, Kadowaki T. Tamemoto H, et al. Among authors: tobe k. Ann N Y Acad Sci. 1997 Sep 20;827:85-93. doi: 10.1111/j.1749-6632.1997.tb51823.x. Ann N Y Acad Sci. 1997. PMID: 9329743 Review. No abstract available.

6

Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes.

Seko Y, Takahashi N, Tobe K, Kadowaki T, Yazaki Y. Seko Y, et al. Among authors: tobe k. Biochem Biophys Res Commun. 1997 Oct 29;239(3):840-4. doi: 10.1006/bbrc.1997.7570. Biochem Biophys Res Commun. 1997. PMID: 9367856

7

[Defects in insulin's signalling process and diabetes mellitus].

Tobe K, Kadowaki T. Tobe K, et al. Nihon Rinsho. 1997 Oct;55 Suppl:328-42. Nihon Rinsho. 1997. PMID: 9392128 Review. Japanese. No abstract available.

8

Pulsatile stretch activates mitogen-activated protein kinase (MAPK) family members and focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes.

Seko Y, Takahashi N, Tobe K, Kadowaki T, Yazaki Y. Seko Y, et al. Among authors: tobe k. Biochem Biophys Res Commun. 1999 May 27;259(1):8-14. doi: 10.1006/bbrc.1999.0720. Biochem Biophys Res Commun. 1999. PMID: 10334907

9

Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes.

Seko Y, Takahashi N, Sabe H, Tobe K, Kadowaki T, Nagai R. Seko Y, et al. Among authors: tobe k. Biochem Biophys Res Commun. 1999 Aug 19;262(1):290-6. doi: 10.1006/bbrc.1999.1185. Biochem Biophys Res Commun. 1999. PMID: 10448107

10

Antibody-mediated insulin resistance treated by cessation of insulin administration.

Hara K, Tobe K, Uchigata Y, Nakazono M, Yasuda K, Terauchi Y, Iwamoto Y, Akanuma Y, Kimura S, Kadowaki T. Hara K, et al. Among authors: tobe k. Intern Med. 2000 Feb;39(2):143-5. doi: 10.2169/internalmedicine.39.143. Intern Med. 2000. PMID: 10732832 Free article.

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