Semaphorin 3A binds to the perineuronal nets via chondroitin sulfate type E motifs in rodent brains.
Dick G, Tan CL, Alves JN, Ehlert EME, Miller GM, Hsieh-Wilson LC, Sugahara K, Oosterhof A, van Kuppevelt TH, Verhaagen J, Fawcett JW, Kwok JCF.
Dick G, et al.
J Biol Chem. 2013 Sep 20;288(38):27384-27395. doi: 10.1074/jbc.M111.310029. Epub 2013 Aug 12.
J Biol Chem. 2013.
PMID: 23940048
Free PMC article.
Recently, we have shown that semaphorin3A (Sema3A), a repulsive axon guidance molecule, localizes to the PNNs and is removed by chondroitinase ABC treatment (Vo, T., Carulli, D., Ehlert, E. M., Kwok, J. C., Dick, G., Mecollari, V., Moloney, E. B., Neufeld, G. …
Recently, we have shown that semaphorin3A (Sema3A), a repulsive axon guidance molecule, localizes to the PNNs and is removed by chondroitina …