Gago F - Search Results

1

Inhibitory effects of marine-derived DNA-binding anti-tumour tetrahydroisoquinolines on the Fanconi anaemia pathway.

Martínez S, Pérez L, Galmarini CM, Aracil M, Tercero JC, Gago F, Albella B, Bueren JA. Martínez S, et al. Among authors: gago f. Br J Pharmacol. 2013 Oct;170(4):871-82. doi: 10.1111/bph.12331. Br J Pharmacol. 2013. PMID: 23937566 Free PMC article.

2

Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin.

Casado JA, Río P, Marco E, García-Hernández V, Domingo A, Pérez L, Tercero JC, Vaquero JJ, Albella B, Gago F, Bueren JA. Casado JA, et al. Among authors: gago f. Mol Cancer Ther. 2008 May;7(5):1309-18. doi: 10.1158/1535-7163.MCT-07-2432. Mol Cancer Ther. 2008. PMID: 18483318

3

Molecular pharmacology and antitumor activity of Zalypsis in several human cancer cell lines.

Leal JF, García-Hernández V, Moneo V, Domingo A, Bueren-Calabuig JA, Negri A, Gago F, Guillén-Navarro MJ, Avilés P, Cuevas C, García-Fernández LF, Galmarini CM. Leal JF, et al. Among authors: gago f. Biochem Pharmacol. 2009 Jul 15;78(2):162-70. doi: 10.1016/j.bcp.2009.04.003. Epub 2009 Apr 11. Biochem Pharmacol. 2009. PMID: 19427997

4

Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival.

Losada A, Muñoz-Alonso MJ, Martínez-Díez M, Gago F, Domínguez JM, Martínez-Leal JF, Galmarini CM. Losada A, et al. Among authors: gago f. Br J Cancer. 2018 Nov;119(11):1410-1420. doi: 10.1038/s41416-018-0336-y. Epub 2018 Nov 13. Br J Cancer. 2018. PMID: 30420615 Free PMC article.

5

PM01183, a new DNA minor groove covalent binder with potent in vitro and in vivo anti-tumour activity.

Leal JF, Martínez-Díez M, García-Hernández V, Moneo V, Domingo A, Bueren-Calabuig JA, Negri A, Gago F, Guillén-Navarro MJ, Avilés P, Cuevas C, García-Fernández LF, Galmarini CM. Leal JF, et al. Among authors: gago f. Br J Pharmacol. 2010 Nov;161(5):1099-110. doi: 10.1111/j.1476-5381.2010.00945.x. Br J Pharmacol. 2010. PMID: 20977459 Free PMC article.

6

Temperature-induced melting of double-stranded DNA in the absence and presence of covalently bonded antitumour drugs: insight from molecular dynamics simulations.

Bueren-Calabuig JA, Giraudon C, Galmarini CM, Egly JM, Gago F. Bueren-Calabuig JA, et al. Among authors: gago f. Nucleic Acids Res. 2011 Oct;39(18):8248-57. doi: 10.1093/nar/gkr512. Epub 2011 Jul 3. Nucleic Acids Res. 2011. PMID: 21727089 Free PMC article.

7

XPF-dependent DNA breaks and RNA polymerase II arrest induced by antitumor DNA interstrand crosslinking-mimetic alkaloids.

Feuerhahn S, Giraudon C, Martínez-Díez M, Bueren-Calabuig JA, Galmarini CM, Gago F, Egly JM. Feuerhahn S, et al. Among authors: gago f. Chem Biol. 2011 Aug 26;18(8):988-99. doi: 10.1016/j.chembiol.2011.06.007. Chem Biol. 2011. PMID: 21867914

8

Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin.

Losada A, Muñoz-Alonso MJ, García C, Sánchez-Murcia PA, Martínez-Leal JF, Domínguez JM, Lillo MP, Gago F, Galmarini CM. Losada A, et al. Among authors: gago f. Sci Rep. 2016 Oct 7;6:35100. doi: 10.1038/srep35100. Sci Rep. 2016. PMID: 27713531 Free PMC article.

9

DNA structural similarity in the 2:1 complexes of the antitumor drugs trabectedin (Yondelis) and chromomycin A3 with an oligonucleotide sequence containing two adjacent TGG binding sites on opposing strands.

Marco E, Gago F. Marco E, et al. Among authors: gago f. Mol Pharmacol. 2005 Dec;68(6):1559-67. doi: 10.1124/mol.105.015685. Epub 2005 Sep 8. Mol Pharmacol. 2005. PMID: 16150929

10

Comparison of ultra-fast 2D and 3D ligand and target descriptors for side effect prediction and network analysis in polypharmacology.

Cortés-Cabrera A, Morris GM, Finn PW, Morreale A, Gago F. Cortés-Cabrera A, et al. Among authors: gago f. Br J Pharmacol. 2013 Oct;170(3):557-67. doi: 10.1111/bph.12294. Br J Pharmacol. 2013. PMID: 23826885 Free PMC article.

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