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Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability.
Abbott KL, Ali A, Reinfeld BI, Deik A, Subudhi S, Landis MD, Hongo RA, Young KL, Kunchok T, Nabel CS, Crowder KD, Kent JR, Madariaga MLL, Jain RK, Beckermann KE, Lewis CA, Clish CB, Muir A, Rathmell WK, Rathmell J, Vander Heiden MG. Abbott KL, et al. Among authors: vander heiden mg. Elife. 2024 May 24;13:RP95652. doi: 10.7554/eLife.95652. Elife. 2024. PMID: 38787918 Free PMC article.
Unprocessed genomic uracil as a source of DNA replication stress in cancer cells.
Saxena S, Nabel CS, Seay TW, Patel PS, Kawale AS, Crosby CR, Tigro H, Oh E, Vander Heiden MG, Hata AN, Suo Z, Zou L. Saxena S, et al. Among authors: vander heiden mg. Mol Cell. 2024 Apr 22:S1097-2765(24)00282-X. doi: 10.1016/j.molcel.2024.04.004. Online ahead of print. Mol Cell. 2024. PMID: 38688279
Effects of aging on glucose and lipid metabolism in mice.
Lien EC, Vu N, Westermark AM, Danai LV, Lau AN, Gültekin Y, Kukurugya MA, Bennett BD, Vander Heiden MG. Lien EC, et al. Among authors: vander heiden mg. bioRxiv [Preprint]. 2023 Dec 18:2023.12.17.572088. doi: 10.1101/2023.12.17.572088. bioRxiv. 2023. PMID: 38187759 Free PMC article. Preprint.
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability.
Abbott KL, Ali A, Reinfeld BI, Deik A, Subudhi S, Landis MD, Hongo RA, Young KL, Kunchok T, Nabel CS, Crowder KD, Kent JR, Madariaga MLL, Jain RK, Beckermann KE, Lewis CA, Clish CB, Muir A, Rathmell WK, Rathmell JC, Vander Heiden MG. Abbott KL, et al. Among authors: vander heiden mg. bioRxiv [Preprint]. 2024 Apr 8:2023.12.24.573250. doi: 10.1101/2023.12.24.573250. bioRxiv. 2024. PMID: 38187626 Free PMC article. Preprint.
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening.
Ramos A, Koch CE, Liu-Lupo Y, Hellinger RD, Kyung T, Abbott KL, Fröse J, Goulet D, Gordon KS, Eidell KP, Leclerc P, Whittaker CA, Larson RC, Muscato AJ, Yates KB, Dubrot J, Doench JG, Regev A, Vander Heiden MG, Maus MV, Manguso RT, Birnbaum ME, Hemann MT. Ramos A, et al. Among authors: vander heiden mg. Nat Commun. 2023 Dec 5;14(1):8048. doi: 10.1038/s41467-023-43790-2. Nat Commun. 2023. PMID: 38052854 Free PMC article.
Cancer immunotherapy responses persist after lymph node resection.
Zhou H, Baish JW, O'Melia MJ, Darragh LB, Specht E, Czapla J, Lei PJ, Menzel L, Rajotte JJ, Nikmaneshi MR, Razavi MS, Vander Heiden MG, Ubellacker JM, Munn LL, Boland GM, Cohen S, Karam SD, Padera TP. Zhou H, et al. Among authors: vander heiden mg. bioRxiv [Preprint]. 2024 Mar 1:2023.09.19.558262. doi: 10.1101/2023.09.19.558262. bioRxiv. 2024. PMID: 37781599 Free PMC article. Preprint.
Manipulating mitochondrial electron flow enhances tumor immunogenicity.
Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Moltó PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Mangalhara KC, et al. Among authors: vander heiden mg. Science. 2023 Sep 22;381(6664):1316-1323. doi: 10.1126/science.abq1053. Epub 2023 Sep 21. Science. 2023. PMID: 37733872 Free PMC article.
239 results