Tanaka T - Search Results

1

Cell-permeable stapled peptides based on HIV-1 integrase inhibitors derived from HIV-1 gene products.

Nomura W, Aikawa H, Ohashi N, Urano E, Métifiot M, Fujino M, Maddali K, Ozaki T, Nozue A, Narumi T, Hashimoto C, Tanaka T, Pommier Y, Yamamoto N, Komano JA, Murakami T, Tamamura H. Nomura W, et al. Among authors: tanaka t. ACS Chem Biol. 2013 Oct 18;8(10):2235-44. doi: 10.1021/cb400495h. Epub 2013 Aug 15. ACS Chem Biol. 2013. PMID: 23898787 Free PMC article.

2

Peptide HIV-1 integrase inhibitors from HIV-1 gene products.

Suzuki S, Urano E, Hashimoto C, Tsutsumi H, Nakahara T, Tanaka T, Nakanishi Y, Maddali K, Han Y, Hamatake M, Miyauchi K, Pommier Y, Beutler JA, Sugiura W, Fuji H, Hoshino T, Itotani K, Nomura W, Narumi T, Yamamoto N, Komano JA, Tamamura H. Suzuki S, et al. Among authors: tanaka t. J Med Chem. 2010 Jul 22;53(14):5356-60. doi: 10.1021/jm1003528. J Med Chem. 2010. PMID: 20586421 Free PMC article.

3

Peptidic HIV integrase inhibitors derived from HIV gene products: structure-activity relationship studies.

Suzuki S, Maddali K, Hashimoto C, Urano E, Ohashi N, Tanaka T, Ozaki T, Arai H, Tsutsumi H, Narumi T, Nomura W, Yamamoto N, Pommier Y, Komano JA, Tamamura H. Suzuki S, et al. Among authors: tanaka t. Bioorg Med Chem. 2010 Sep 15;18(18):6771-5. doi: 10.1016/j.bmc.2010.07.050. Epub 2010 Jul 25. Bioorg Med Chem. 2010. PMID: 20708407 Free PMC article.

4

Conjugation of cell-penetrating peptides leads to identification of anti-HIV peptides from matrix proteins.

Narumi T, Komoriya M, Hashimoto C, Wu H, Nomura W, Suzuki S, Tanaka T, Chiba J, Yamamoto N, Murakami T, Tamamura H. Narumi T, et al. Among authors: tanaka t. Bioorg Med Chem. 2012 Feb 15;20(4):1468-74. doi: 10.1016/j.bmc.2011.12.055. Epub 2012 Jan 2. Bioorg Med Chem. 2012. PMID: 22277590

5

Fluorophore labeling enables imaging and evaluation of specific CXCR4-ligand interaction at the cell membrane for fluorescence-based screening.

Nomura W, Tanabe Y, Tsutsumi H, Tanaka T, Ohba K, Yamamoto N, Tamamura H. Nomura W, et al. Among authors: tanaka t. Bioconjug Chem. 2008 Sep;19(9):1917-20. doi: 10.1021/bc800216p. Epub 2008 Aug 16. Bioconjug Chem. 2008. PMID: 18707146

6

Structure-activity relationship study of CXCR4 antagonists bearing the cyclic pentapeptide scaffold: identification of the new pharmacophore.

Tanaka T, Tsutsumi H, Nomura W, Tanabe Y, Ohashi N, Esaka A, Ochiai C, Sato J, Itotani K, Murakami T, Ohba K, Yamamoto N, Fujii N, Tamamura H. Tanaka T, et al. Org Biomol Chem. 2008 Dec 7;6(23):4374-7. doi: 10.1039/b812029c. Epub 2008 Oct 17. Org Biomol Chem. 2008. PMID: 19005596

7

Fluorogenically active leucine zipper peptides as tag-probe pairs for protein imaging in living cells.

Tsutsumi H, Nomura W, Abe S, Mino T, Masuda A, Ohashi N, Tanaka T, Ohba K, Yamamoto N, Akiyoshi K, Tamamura H. Tsutsumi H, et al. Among authors: tanaka t. Angew Chem Int Ed Engl. 2009;48(48):9164-6. doi: 10.1002/anie.200903183. Angew Chem Int Ed Engl. 2009. PMID: 19876989 No abstract available.

8

CD4 mimics targeting the mechanism of HIV entry.

Yamada Y, Ochiai C, Yoshimura K, Tanaka T, Ohashi N, Narumi T, Nomura W, Harada S, Matsushita S, Tamamura H. Yamada Y, et al. Among authors: tanaka t. Bioorg Med Chem Lett. 2010 Jan 1;20(1):354-8. doi: 10.1016/j.bmcl.2009.10.098. Epub 2009 Nov 4. Bioorg Med Chem Lett. 2010. PMID: 19926478

9

Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies.

Nakahara T, Nomura W, Ohba K, Ohya A, Tanaka T, Hashimoto C, Narumi T, Murakami T, Yamamoto N, Tamamura H. Nakahara T, et al. Among authors: tanaka t. Bioconjug Chem. 2010 Apr 21;21(4):709-14. doi: 10.1021/bc900502z. Bioconjug Chem. 2010. PMID: 20359196

10

CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist.

Narumi T, Ochiai C, Yoshimura K, Harada S, Tanaka T, Nomura W, Arai H, Ozaki T, Ohashi N, Matsushita S, Tamamura H. Narumi T, et al. Among authors: tanaka t. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5853-8. doi: 10.1016/j.bmcl.2010.07.106. Epub 2010 Aug 3. Bioorg Med Chem Lett. 2010. PMID: 20728351

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