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The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells.
Cheng YY, Yang JS, Tsai SC, Liaw CC, Chung JG, Huang LJ, Lee KH, Lu CC, Chien HC, Tsuzuki M, Kuo SC. Cheng YY, et al. Among authors: tsuzuki m. Oncol Rep. 2012 Oct;28(4):1482-90. doi: 10.3892/or.2012.1923. Epub 2012 Jul 19. Oncol Rep. 2012. PMID: 22825350
Bufalin induces G0/G1 phase arrest through inhibiting the levels of cyclin D, cyclin E, CDK2 and CDK4, and triggers apoptosis via mitochondrial signaling pathway in T24 human bladder cancer cells.
Huang WW, Yang JS, Pai SJ, Wu PP, Chang SJ, Chueh FS, Fan MJ, Chiou SM, Kuo HM, Yeh CC, Chen PY, Tsuzuki M, Chung JG. Huang WW, et al. Among authors: tsuzuki m. Mutat Res. 2012 Apr 1;732(1-2):26-33. doi: 10.1016/j.mrfmmm.2011.09.010. Epub 2012 Jan 20. Mutat Res. 2012. PMID: 22285700
Activations of Both Extrinsic and Intrinsic Pathways in HCT 116 Human Colorectal Cancer Cells Contribute to Apoptosis through p53-Mediated ATM/Fas Signaling by Emilia sonchifolia Extract, a Folklore Medicinal Plant.
Lan YH, Chiang JH, Huang WW, Lu CC, Chung JG, Wu TS, Jhan JH, Lin KL, Pai SJ, Chiu YJ, Tsuzuki M, Yang JS. Lan YH, et al. Among authors: tsuzuki m. Evid Based Complement Alternat Med. 2012;2012:178178. doi: 10.1155/2012/178178. Epub 2012 Feb 28. Evid Based Complement Alternat Med. 2012. PMID: 22474491 Free PMC article.
Cucurbitacin E Induces G(2)/M Phase Arrest through STAT3/p53/p21 Signaling and Provokes Apoptosis via Fas/CD95 and Mitochondria-Dependent Pathways in Human Bladder Cancer T24 Cells.
Huang WW, Yang JS, Lin MW, Chen PY, Chiou SM, Chueh FS, Lan YH, Pai SJ, Tsuzuki M, Ho WJ, Chung JG. Huang WW, et al. Among authors: tsuzuki m. Evid Based Complement Alternat Med. 2012;2012:952762. doi: 10.1155/2012/952762. Epub 2012 Jan 9. Evid Based Complement Alternat Med. 2012. PMID: 22272214 Free PMC article.
363 results