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A mouse model for human norovirus.
Taube S, Kolawole AO, Höhne M, Wilkinson JE, Handley SA, Perry JW, Thackray LB, Akkina R, Wobus CE. Taube S, et al. Among authors: handley sa. mBio. 2013 Jul 16;4(4):e00450-13. doi: 10.1128/mBio.00450-13. mBio. 2013. PMID: 23860770 Free PMC article.
Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome.
Handley SA, Thackray LB, Zhao G, Presti R, Miller AD, Droit L, Abbink P, Maxfield LF, Kambal A, Duan E, Stanley K, Kramer J, Macri SC, Permar SR, Schmitz JE, Mansfield K, Brenchley JM, Veazey RS, Stappenbeck TS, Wang D, Barouch DH, Virgin HW. Handley SA, et al. Cell. 2012 Oct 12;151(2):253-66. doi: 10.1016/j.cell.2012.09.024. Cell. 2012. PMID: 23063120 Free PMC article.
Tropism for tuft cells determines immune promotion of norovirus pathogenesis.
Wilen CB, Lee S, Hsieh LL, Orchard RC, Desai C, Hykes BL Jr, McAllaster MR, Balce DR, Feehley T, Brestoff JR, Hickey CA, Yokoyama CC, Wang YT, MacDuff DA, Kreamalmayer D, Howitt MR, Neil JA, Cadwell K, Allen PM, Handley SA, van Lookeren Campagne M, Baldridge MT, Virgin HW. Wilen CB, et al. Among authors: handley sa. Science. 2018 Apr 13;360(6385):204-208. doi: 10.1126/science.aar3799. Science. 2018. PMID: 29650672 Free PMC article.
The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis.
Winkler ES, Shrihari S, Hykes BL Jr, Handley SA, Andhey PS, Huang YS, Swain A, Droit L, Chebrolu KK, Mack M, Vanlandingham DL, Thackray LB, Cella M, Colonna M, Artyomov MN, Stappenbeck TS, Diamond MS. Winkler ES, et al. Among authors: handley sa. Cell. 2020 Aug 20;182(4):901-918.e18. doi: 10.1016/j.cell.2020.06.029. Epub 2020 Jul 14. Cell. 2020. PMID: 32668198 Free PMC article.
A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis.
Lee S, Liu H, Wilen CB, Sychev ZE, Desai C, Hykes BL Jr, Orchard RC, McCune BT, Kim KW, Nice TJ, Handley SA, Baldridge MT, Amarasinghe GK, Virgin HW. Lee S, et al. Among authors: handley sa. Cell Host Microbe. 2019 Jun 12;25(6):845-857.e5. doi: 10.1016/j.chom.2019.04.005. Epub 2019 May 23. Cell Host Microbe. 2019. PMID: 31130511 Free PMC article.
93 results