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Discovery of GLPG2737, a Potent Type 2 Corrector of CFTR for the Treatment of Cystic Fibrosis in Combination with a Potentiator and a Type 1 Co-corrector.
Pizzonero M, Akkari R, Bock X, Gosmini R, De Lemos E, Duthion B, Newsome G, Mai TT, Roques V, Jary H, Lefrancois JM, Cherel L, Quenehen V, Babel M, Merayo N, Bienvenu N, Mammoliti O, Coti G, Palisse A, Cowart M, Shrestha A, Greszler S, Van Der Plas S, Jansen K, Claes P, Jans M, Gees M, Borgonovi M, De Wilde G, Conrath K. Pizzonero M, et al. Among authors: jans m. J Med Chem. 2024 Apr 11;67(7):5216-5232. doi: 10.1021/acs.jmedchem.3c01790. Epub 2024 Mar 25. J Med Chem. 2024. PMID: 38527911 Free PMC article.
Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease.
Srinivasan S, Kancheva D, De Ren S, Saito T, Jans M, Boone F, Vandendriessche C, Paesmans I, Maurin H, Vandenbroucke RE, Hoste E, Voet S, Scheyltjens I, Pavie B, Lippens S, Schwabenland M, Prinz M, Saido T, Bottelbergs A, Movahedi K, Lamkanfi M, van Loo G. Srinivasan S, et al. Among authors: jans m. Front Immunol. 2024 Jan 29;15:1323409. doi: 10.3389/fimmu.2024.1323409. eCollection 2024. Front Immunol. 2024. PMID: 38352874 Free PMC article.
Estimating Web Survey Mode and Panel Effects in a Nationwide Survey of Alcohol Use.
ZuWallack R, Jans M, Brassell T, Bailly K, Dayton J, Martinez P, Patterson D, Greenfield TK, Karriker-Jaffe KJ. ZuWallack R, et al. Among authors: jans m. J Surv Stat Methodol. 2022 Nov 2;11(5):1089-1109. doi: 10.1093/jssam/smac028. eCollection 2023 Nov. J Surv Stat Methodol. 2022. PMID: 38028817 Free PMC article. Review.
Sterile triggers drive joint inflammation in TNF- and IL-1β-dependent mouse arthritis models.
Thiran A, Petta I, Blancke G, Thorp M, Planckaert G, Jans M, Andries V, Barbry K, Gilis E, Coudenys J, Hochepied T, Vanhove C, Gracey E, Dumas E, Manuelo T, Josipovic I, van Loo G, Elewaut D, Vereecke L. Thiran A, et al. Among authors: jans m. EMBO Mol Med. 2023 Oct 11;15(10):e17691. doi: 10.15252/emmm.202317691. Epub 2023 Sep 11. EMBO Mol Med. 2023. PMID: 37694693 Free PMC article.
Human skin stem cell-derived hepatic cells as in vitro drug discovery model for insulin-driven de novo lipogenesis.
Buyl K, Vrints M, Fernando R, Desmae T, Van Eeckhoutte T, Jans M, Van Der Schueren J, Boeckmans J, Rodrigues RM, De Boe V, Rogiers V, De Kock J, Beirinckx F, Vanhaecke T. Buyl K, et al. Among authors: jans m. Eur J Pharmacol. 2023 Oct 15;957:175989. doi: 10.1016/j.ejphar.2023.175989. Epub 2023 Aug 11. Eur J Pharmacol. 2023. PMID: 37572939 Free article.
The results of concentration of care: Surgical outcomes of neuroblastoma in the Netherlands.
van der Steeg AFW, Jans M, Tytgat G, Fiocco MF, van de Ven C, Terwisscha van Scheltinga CEJ, Pieters R, van Noesel MM, van Dijk AH, Hulsker CCC, Wijnen MHWA. van der Steeg AFW, et al. Among authors: jans m. Eur J Surg Oncol. 2023 Feb;49(2):505-511. doi: 10.1016/j.ejso.2022.10.005. Epub 2022 Oct 18. Eur J Surg Oncol. 2023. PMID: 36307270 Free article.
Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer.
Villar VH, Allega MF, Deshmukh R, Ackermann T, Nakasone MA, Vande Voorde J, Drake TM, Oetjen J, Bloom A, Nixon C, Müller M, May S, Tan EH, Vereecke L, Jans M, Blancke G, Murphy DJ, Huang DT, Lewis DY, Bird TG, Sansom OJ, Blyth K, Sumpton D, Tardito S. Villar VH, et al. Among authors: jans m. Nat Chem Biol. 2023 Mar;19(3):292-300. doi: 10.1038/s41589-022-01154-9. Epub 2022 Oct 24. Nat Chem Biol. 2023. PMID: 36280791 Free PMC article.
53 results