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Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays.
Kiselyov AS, Semenova MN, Chernyshova NB, Leitao A, Samet AV, Kislyi KA, Raihstat MM, Oprea T, Lemcke H, Lantow M, Weiss DG, Ikizalp NN, Kuznetsov SA, Semenov VV. Kiselyov AS, et al. Among authors: lemcke h. Eur J Med Chem. 2010 May;45(5):1683-97. doi: 10.1016/j.ejmech.2009.12.072. Epub 2010 Jan 14. Eur J Med Chem. 2010. PMID: 20110137
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