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Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis.
Phetsuksiri B, Jackson M, Scherman H, McNeil M, Besra GS, Baulard AR, Slayden RA, DeBarber AE, Barry CE 3rd, Baird MS, Crick DC, Brennan PJ. Phetsuksiri B, et al. Among authors: brennan pj. J Biol Chem. 2003 Dec 26;278(52):53123-30. doi: 10.1074/jbc.M311209200. Epub 2003 Oct 14. J Biol Chem. 2003. PMID: 14559907 Free PMC article.
A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone.
Grzegorzewicz AE, Korduláková J, Jones V, Born SE, Belardinelli JM, Vaquié A, Gundi VA, Madacki J, Slama N, Laval F, Vaubourgeix J, Crew RM, Gicquel B, Daffé M, Morbidoni HR, Brennan PJ, Quémard A, McNeil MR, Jackson M. Grzegorzewicz AE, et al. Among authors: brennan pj. J Biol Chem. 2012 Nov 9;287(46):38434-41. doi: 10.1074/jbc.M112.400994. Epub 2012 Sep 21. J Biol Chem. 2012. PMID: 23002234 Free PMC article.
Assembling of the Mycobacterium tuberculosis Cell Wall Core.
Grzegorzewicz AE, de Sousa-d'Auria C, McNeil MR, Huc-Claustre E, Jones V, Petit C, Angala SK, Zemanová J, Wang Q, Belardinelli JM, Gao Q, Ishizaki Y, Mikušová K, Brennan PJ, Ronning DR, Chami M, Houssin C, Jackson M. Grzegorzewicz AE, et al. Among authors: brennan pj. J Biol Chem. 2016 Sep 2;291(36):18867-79. doi: 10.1074/jbc.M116.739227. Epub 2016 Jul 14. J Biol Chem. 2016. PMID: 27417139 Free PMC article.
569 results