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Omega 6 to omega 3 fatty acid imbalance early in life leads to persistent reductions in DHA levels in glycerophospholipids in rat hypothalamus even after long-term omega 3 fatty acid repletion.
Li D, Weisinger HS, Weisinger RS, Mathai M, Armitage JA, Vingrys AJ, Sinclair AJ. Li D, et al. Prostaglandins Leukot Essent Fatty Acids. 2006 Jun;74(6):391-9. doi: 10.1016/j.plefa.2006.03.010. Epub 2006 May 23. Prostaglandins Leukot Essent Fatty Acids. 2006. PMID: 16716580
Methylenetetrahydrofolate reductase variants associated with hypertension and cardiovascular disease interact with dietary polyunsaturated fatty acids to modulate plasma homocysteine in puerto rican adults.
Huang T, Tucker KL, Lee YC, Crott JW, Parnell LD, Shen J, Smith CE, Ordovas JM, Li D, Lai CQ. Huang T, et al. Among authors: li d. J Nutr. 2011 Apr 1;141(4):654-9. doi: 10.3945/jn.110.134353. Epub 2011 Jan 26. J Nutr. 2011. PMID: 21270364 Free PMC article.
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