Gan HK - Search Results

1

The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered.

Gan HK, Cvrljevic AN, Johns TG. Gan HK, et al. FEBS J. 2013 Nov;280(21):5350-70. doi: 10.1111/febs.12393. Epub 2013 Jul 8. FEBS J. 2013. PMID: 23777544 Free article. Review.

2

Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR.

Panousis C, Rayzman VM, Johns TG, Renner C, Liu Z, Cartwright G, Lee FT, Wang D, Gan H, Cao D, Kypridis A, Smyth FE, Brechbiel MW, Burgess AW, Old LJ, Scott AM. Panousis C, et al. Br J Cancer. 2005 Mar 28;92(6):1069-77. doi: 10.1038/sj.bjc.6602470. Br J Cancer. 2005. PMID: 15770208 Free PMC article.

3

Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity.

Perera RM, Narita Y, Furnari FB, Gan HK, Murone C, Ahlkvist M, Luwor RB, Burgess AW, Stockert E, Jungbluth AA, Old LJ, Cavenee WK, Scott AM, Johns TG. Perera RM, et al. Among authors: gan hk. Clin Cancer Res. 2005 Sep 1;11(17):6390-9. doi: 10.1158/1078-0432.CCR-04-2653. Clin Cancer Res. 2005. PMID: 16144944

4

The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806.

Gan HK, Walker F, Burgess AW, Rigopoulos A, Scott AM, Johns TG. Gan HK, et al. J Biol Chem. 2007 Feb 2;282(5):2840-50. doi: 10.1074/jbc.M605136200. Epub 2006 Nov 8. J Biol Chem. 2007. PMID: 17092939 Free article.

5

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR.

Garrett TP, Burgess AW, Gan HK, Luwor RB, Cartwright G, Walker F, Orchard SG, Clayton AH, Nice EC, Rothacker J, Catimel B, Cavenee WK, Old LJ, Stockert E, Ritter G, Adams TE, Hoyne PA, Wittrup D, Chao G, Cochran JR, Luo C, Lou M, Huyton T, Xu Y, Fairlie WD, Yao S, Scott AM, Johns TG. Garrett TP, et al. Among authors: gan hk. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5082-7. doi: 10.1073/pnas.0811559106. Epub 2009 Mar 16. Proc Natl Acad Sci U S A. 2009. PMID: 19289842 Free PMC article.

6

Targeting a unique EGFR epitope with monoclonal antibody 806 activates NF-kappaB and initiates tumour vascular normalization.

Gan HK, Lappas M, Cao DX, Cvrljevdic A, Scott AM, Johns TG. Gan HK, et al. J Cell Mol Med. 2009 Sep;13(9B):3993-4001. doi: 10.1111/j.1582-4934.2009.00783.x. Epub 2009 May 11. J Cell Mol Med. 2009. PMID: 19432811 Free PMC article.

7

Immuno-PET quantitation of de2-7 epidermal growth factor receptor expression in glioma using 124I-IMP-R4-labeled antibody ch806.

Lee FT, O'Keefe GJ, Gan HK, Mountain AJ, Jones GR, Saunder TH, Sagona J, Rigopoulos A, Smyth FE, Johns TG, Govindan SV, Goldenberg DM, Old LJ, Scott AM. Lee FT, et al. Among authors: gan hk. J Nucl Med. 2010 Jun;51(6):967-72. doi: 10.2967/jnumed.109.068395. Epub 2010 May 19. J Nucl Med. 2010. PMID: 20484439 Free article.

8

MAb 806 enhances the efficacy of ionizing radiation in glioma xenografts expressing the de2-7 epidermal growth factor receptor.

Johns TG, McKay MJ, Cvrljevic AN, Gan HK, Taylor C, Xu H, Smyth FE, Scott AM. Johns TG, et al. Among authors: gan hk. Int J Radiat Oncol Biol Phys. 2010 Oct 1;78(2):572-8. doi: 10.1016/j.ijrobp.2010.03.027. Epub 2010 Jul 16. Int J Radiat Oncol Biol Phys. 2010. PMID: 20638193

9

Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy.

Gan HK, Burgess AW, Clayton AH, Scott AM. Gan HK, et al. Cancer Res. 2012 Jun 15;72(12):2924-30. doi: 10.1158/0008-5472.CAN-11-3898. Epub 2012 Jun 1. Cancer Res. 2012. PMID: 22659454 Review.

10

Quantitative intratumoural microdistribution and kinetics of (131)I-huA33 antibody in patients with colorectal carcinoma.

Ciprotti M, Chong G, Gan HK, Chan A, Murone C, MacGregor D, Lee FT, Johns TG, Heath JK, Ernst M, Burgess AW, Scott AM. Ciprotti M, et al. Among authors: gan hk. EJNMMI Res. 2014 May 30;4:22. doi: 10.1186/s13550-014-0022-x. eCollection 2014. EJNMMI Res. 2014. PMID: 24995151 Free PMC article.

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