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Polymorphic fibrillation of the destabilized fourth fasciclin-1 domain mutant A546T of the Transforming growth factor-β-induced protein (TGFBIp) occurs through multiple pathways with different oligomeric intermediates.
Andreasen M, Nielsen SB, Runager K, Christiansen G, Nielsen NC, Enghild JJ, Otzen DE. Andreasen M, et al. Among authors: christiansen g. J Biol Chem. 2012 Oct 5;287(41):34730-42. doi: 10.1074/jbc.M112.379552. Epub 2012 Aug 14. J Biol Chem. 2012. PMID: 22893702 Free PMC article.
How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro.
Lorenzen N, Nielsen SB, Yoshimura Y, Vad BS, Andersen CB, Betzer C, Kaspersen JD, Christiansen G, Pedersen JS, Jensen PH, Mulder FA, Otzen DE. Lorenzen N, et al. Among authors: christiansen g. J Biol Chem. 2014 Aug 1;289(31):21299-310. doi: 10.1074/jbc.M114.554667. Epub 2014 Jun 6. J Biol Chem. 2014. PMID: 24907278 Free PMC article.
How Glycosaminoglycans Promote Fibrillation of Salmon Calcitonin.
Malmos KG, Bjerring M, Jessen CM, Nielsen EH, Poulsen ET, Christiansen G, Vosegaard T, Skrydstrup T, Enghild JJ, Pedersen JS, Otzen DE. Malmos KG, et al. Among authors: christiansen g. J Biol Chem. 2016 Aug 5;291(32):16849-62. doi: 10.1074/jbc.M116.715466. Epub 2016 Jun 8. J Biol Chem. 2016. PMID: 27281819 Free PMC article.
Branching in amyloid fibril growth.
Andersen CB, Yagi H, Manno M, Martorana V, Ban T, Christiansen G, Otzen DE, Goto Y, Rischel C. Andersen CB, et al. Among authors: christiansen g. Biophys J. 2009 Feb 18;96(4):1529-36. doi: 10.1016/j.bpj.2008.11.024. Biophys J. 2009. PMID: 19217869 Free PMC article.
The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.
Lorenzen N, Nielsen SB, Buell AK, Kaspersen JD, Arosio P, Vad BS, Paslawski W, Christiansen G, Valnickova-Hansen Z, Andreasen M, Enghild JJ, Pedersen JS, Dobson CM, Knowles TP, Otzen DE. Lorenzen N, et al. Among authors: christiansen g. J Am Chem Soc. 2014 Mar 12;136(10):3859-68. doi: 10.1021/ja411577t. Epub 2014 Feb 28. J Am Chem Soc. 2014. PMID: 24527756
340 results