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PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.
Lindgren AE, Karlberg T, Thorsell AG, Hesse M, Spjut S, Ekblad T, Andersson CD, Pinto AF, Weigelt J, Hottiger MO, Linusson A, Elofsson M, Schüler H. Lindgren AE, et al. Among authors: schuler h. ACS Chem Biol. 2013 Aug 16;8(8):1698-703. doi: 10.1021/cb4002014. Epub 2013 Jun 25. ACS Chem Biol. 2013. PMID: 23742272
The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch.
Collins R, Karlberg T, Lehtiö L, Schütz P, van den Berg S, Dahlgren LG, Hammarström M, Weigelt J, Schüler H. Collins R, et al. Among authors: schuler h. J Biol Chem. 2009 Apr 17;284(16):10296-300. doi: 10.1074/jbc.C900018200. Epub 2009 Feb 25. J Biol Chem. 2009. PMID: 19244245 Free PMC article.
Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
Lehtiö L, Jemth AS, Collins R, Loseva O, Johansson A, Markova N, Hammarström M, Flores A, Holmberg-Schiavone L, Weigelt J, Helleday T, Schüler H, Karlberg T. Lehtiö L, et al. Among authors: schuler h. J Med Chem. 2009 May 14;52(9):3108-11. doi: 10.1021/jm900052j. J Med Chem. 2009. PMID: 19354255
Toward a unified nomenclature for mammalian ADP-ribosyltransferases.
Hottiger MO, Hassa PO, Lüscher B, Schüler H, Koch-Nolte F. Hottiger MO, et al. Among authors: schuler h. Trends Biochem Sci. 2010 Apr;35(4):208-19. doi: 10.1016/j.tibs.2009.12.003. Epub 2010 Jan 26. Trends Biochem Sci. 2010. PMID: 20106667 Review.
325 results