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Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration.
Nakamura I, Fernandez-Barrena MG, Ortiz-Ruiz MC, Almada LL, Hu C, Elsawa SF, Mills LD, Romecin PA, Gulaid KH, Moser CD, Han JJ, Vrabel A, Hanse EA, Akogyeram NA, Albrecht JH, Monga SPS, Sanderson SO, Prieto J, Roberts LR, Fernandez-Zapico ME. Nakamura I, et al. J Biol Chem. 2013 Jul 19;288(29):21389-21398. doi: 10.1074/jbc.M112.443440. Epub 2013 Jun 5. J Biol Chem. 2013. PMID: 23740243 Free PMC article.
The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation.
Lai JP, Oseini AM, Moser CD, Yu C, Elsawa SF, Hu C, Nakamura I, Han T, Aderca I, Isomoto H, Garrity-Park MM, Shire AM, Li J, Sanderson SO, Adjei AA, Fernandez-Zapico ME, Roberts LR. Lai JP, et al. Among authors: nakamura i. Hepatology. 2010 Nov;52(5):1680-9. doi: 10.1002/hep.23848. Hepatology. 2010. PMID: 20725905 Free PMC article.
Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma.
Dhanasekaran R, Nakamura I, Hu C, Chen G, Oseini AM, Seven ES, Miamen AG, Moser CD, Zhou W, van Kuppevelt TH, van Deursen JM, Mounajjed T, Fernandez-Zapico ME, Roberts LR. Dhanasekaran R, et al. Among authors: nakamura i. Hepatology. 2015 Apr;61(4):1269-83. doi: 10.1002/hep.27658. Epub 2015 Feb 13. Hepatology. 2015. PMID: 25503294 Free PMC article.
Transcriptional Induction of Periostin by a Sulfatase 2-TGFβ1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma.
Chen G, Nakamura I, Dhanasekaran R, Iguchi E, Tolosa EJ, Romecin PA, Vera RE, Almada LL, Miamen AG, Chaiteerakij R, Zhou M, Asiedu MK, Moser CD, Han S, Hu C, Banini BA, Oseini AM, Chen Y, Fang Y, Yang D, Shaleh HM, Wang S, Wu D, Song T, Lee JS, Thorgeirsson SS, Chevet E, Shah VH, Fernandez-Zapico ME, Roberts LR. Chen G, et al. Among authors: nakamura i. Cancer Res. 2017 Feb 1;77(3):632-645. doi: 10.1158/0008-5472.CAN-15-2556. Epub 2016 Nov 21. Cancer Res. 2017. PMID: 27872089 Free PMC article.
1,130 results