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MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis.
International Multiple Sclerosis Genetics Consortium; Lill CM, Schjeide BM, Graetz C, Ban M, Alcina A, Ortiz MA, Pérez J, Damotte V, Booth D, Lopez de Lapuente A, Broer L, Schilling M, Akkad DA, Aktas O, Alloza I, Antigüedad A, Arroyo R, Blaschke P, Buttmann M, Chan A, Compston A, Cournu-Rebeix I, Dörner T, Epplen JT, Fernández Ó, Gerdes LA, Guillot-Noël L, Hartung HP, Hoffjan S, Izquierdo G, Kemppinen A, Kroner A, Kubisch C, Kümpfel T, Li SC, Lindenberger U, Lohse P, Lubetzki C, Luessi F, Malhotra S, Mescheriakova J, Montalban X, Papeix C, Paredes LF, Rieckmann P, Steinhagen-Thiessen E, Winkelmann A, Zettl UK, Hintzen R, Vandenbroeck K, Stewart G, Fontaine B, Comabella M, Urcelay E, Matesanz F, Sawcer S, Bertram L, Zipp F. International Multiple Sclerosis Genetics Consortium, et al. Among authors: urcelay e. Brain. 2013 Jun;136(Pt 6):1778-82. doi: 10.1093/brain/awt101. Brain. 2013. PMID: 23739915 Free PMC article.
Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk.
Cavanillas ML, Alcina A, Núñez C, de las Heras V, Fernández-Arquero M, Bartolomé M, de la Concha EG, Fernández O, Arroyo R, Matesanz F, Urcelay E. Cavanillas ML, et al. Among authors: urcelay e. Eur J Hum Genet. 2010 Jul;18(7):794-9. doi: 10.1038/ejhg.2010.15. Epub 2010 Feb 24. Eur J Hum Genet. 2010. PMID: 20179739 Free PMC article.
STAT3 locus in inflammatory bowel disease and multiple sclerosis susceptibility.
Cénit MC, Alcina A, Márquez A, Mendoza JL, Díaz-Rubio M, de las Heras V, Izquierdo G, Arroyo R, Fernández O, de la Concha EG, Matesanz F, Urcelay E. Cénit MC, et al. Among authors: urcelay e. Genes Immun. 2010 Apr;11(3):264-8. doi: 10.1038/gene.2010.10. Epub 2010 Mar 4. Genes Immun. 2010. PMID: 20200543
Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain.
Swaminathan B, Matesanz F, Cavanillas ML, Alloza I, Otaegui D, Olascoaga J, Cénit MC, de las Heras V, Barcina MG, Arroyo R, Alcina A, Fernandez O, Antigüedad A, Urcelay E, Vandenbroeck K. Swaminathan B, et al. Among authors: urcelay e. J Neuroimmunol. 2010 Jun;223(1-2):100-3. doi: 10.1016/j.jneuroim.2010.03.020. Epub 2010 Apr 28. J Neuroimmunol. 2010. PMID: 20430450
The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis.
Alcina A, Vandenbroeck K, Otaegui D, Saiz A, Gonzalez JR, Fernandez O, Cavanillas ML, Cénit MC, Arroyo R, Alloza I, García-Barcina M, Antigüedad A, Leyva L, Izquierdo G, Lucas M, Fedetz M, Pinto-Medel MJ, Olascoaga J, Blanco Y, Comabella M, Montalban X, Urcelay E, Matesanz F. Alcina A, et al. Among authors: urcelay e. Genes Immun. 2010 Jul;11(5):439-45. doi: 10.1038/gene.2010.30. Epub 2010 May 27. Genes Immun. 2010. PMID: 20508602
CD40: novel association with Crohn's disease and replication in multiple sclerosis susceptibility.
Blanco-Kelly F, Matesanz F, Alcina A, Teruel M, Díaz-Gallo LM, Gómez-García M, López-Nevot MA, Rodrigo L, Nieto A, Cardeña C, Alcain G, Díaz-Rubio M, de la Concha EG, Fernandez O, Arroyo R, Martín J, Urcelay E. Blanco-Kelly F, et al. Among authors: urcelay e. PLoS One. 2010 Jul 12;5(7):e11520. doi: 10.1371/journal.pone.0011520. PLoS One. 2010. PMID: 20634952 Free PMC article.
IFN-beta pharmacogenomics in multiple sclerosis.
Vandenbroeck K, Urcelay E, Comabella M. Vandenbroeck K, et al. Among authors: urcelay e. Pharmacogenomics. 2010 Aug;11(8):1137-48. doi: 10.2217/pgs.10.108. Pharmacogenomics. 2010. PMID: 20712530 Review.
Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus-6 infection.
Vandenbroeck K, Alloza I, Swaminathan B, Antigüedad A, Otaegui D, Olascoaga J, Barcina MG, de las Heras V, Bartolomé M, Fernández-Arquero M, Arroyo R, Alvarez-Lafuente R, Cénit MC, Urcelay E. Vandenbroeck K, et al. Among authors: urcelay e. Genes Immun. 2011 Jan;12(1):40-5. doi: 10.1038/gene.2010.46. Epub 2010 Sep 23. Genes Immun. 2011. PMID: 20861862
211 results