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Page 1
Heterocyclic modification of a novel bicyclo[3.1.0]hexane NPY1 receptor antagonist.
Luo G, Chen L, Hu S, Huang Y, Mattson G, Iben LG, Russell JW, Clarke WJ, Hogan JB, Antal-Zimanyi I, Poindexter GS. Luo G, et al. Among authors: poindexter gs. Bioorg Med Chem Lett. 2013 Jul 1;23(13):3814-7. doi: 10.1016/j.bmcl.2013.04.095. Epub 2013 May 15. Bioorg Med Chem Lett. 2013. PMID: 23726344
Novel dihydropyrazine analogues as NPY antagonists.
Sit SY, Huang Y, Antal-Zimanyi I, Ward S, Poindexter GS. Sit SY, et al. Among authors: poindexter gs. Bioorg Med Chem Lett. 2002 Feb 11;12(3):337-40. doi: 10.1016/s0960-894x(01)00765-x. Bioorg Med Chem Lett. 2002. PMID: 11814791
Dihydropyridine neuropeptide Y Y(1) receptor antagonists.
Poindexter GS, Bruce MA, LeBoulluec KL, Monkovic I, Martin SW, Parker EM, Iben LG, McGovern RT, Ortiz AA, Stanley JA, Mattson GK, Kozlowski M, Arcuri M, Antal-Zimanyi I. Poindexter GS, et al. Bioorg Med Chem Lett. 2002 Feb 11;12(3):379-82. doi: 10.1016/s0960-894x(01)00761-2. Bioorg Med Chem Lett. 2002. PMID: 11814801
Synthesis and evaluation of 5,5-diphenylimidazolones as potent human neuropeptide Y5 receptor antagonists.
Gillman KW, Higgins MA, Poindexter GS, Browning M, Clarke WJ, Flowers S, Grace JE Jr, Hogan JB, McGovern RT, Iben LG, Mattson GK, Ortiz A, Rassnick S, Russell JW, Antal-Zimanyi I. Gillman KW, et al. Among authors: poindexter gs. Bioorg Med Chem. 2006 Aug 15;14(16):5517-26. doi: 10.1016/j.bmc.2006.04.042. Epub 2006 May 11. Bioorg Med Chem. 2006. PMID: 16697206
Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y(1) receptor antagonist.
Antal-Zimanyi I, Bruce MA, Leboulluec KL, Iben LG, Mattson GK, McGovern RT, Hogan JB, Leahy CL, Flowers SC, Stanley JA, Ortiz AA, Poindexter GS. Antal-Zimanyi I, et al. Among authors: poindexter gs. Eur J Pharmacol. 2008 Aug 20;590(1-3):224-32. doi: 10.1016/j.ejphar.2008.06.032. Epub 2008 Jun 12. Eur J Pharmacol. 2008. PMID: 18573246
Discovery of a Novel Class of Bicyclo[3.1.0]hexanylpiperazines as Noncompetitive Neuropeptide Y Y1 Antagonists.
Hu S, Huang Y, Deshpande M, Luo G, Bruce MA, Chen L, Mattson G, Iben LG, Zhang J, Russell JW, Clarke WJ, Hogan JB, Ortiz A, Flint O, Henwood A, Gao Q, Antal-Zimanyi I, Poindexter GS. Hu S, et al. Among authors: poindexter gs. ACS Med Chem Lett. 2012 Jan 4;3(3):222-6. doi: 10.1021/ml200265m. eCollection 2012 Mar 8. ACS Med Chem Lett. 2012. PMID: 24900458 Free PMC article.
beta-alanine dipeptides as MC4R agonists.
Ruel R, Herpin TF, Iben L, Luo G, Martel A, Mason H, Mattson G, Poirier B, Ruediger EH, Shi D, Thibault C, Yu G, Antal Zimanyi I, Poindexter GS, Macor JE. Ruel R, et al. Among authors: poindexter gs. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4341-4. doi: 10.1016/j.bmcl.2003.09.036. Bioorg Med Chem Lett. 2003. PMID: 14643322
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