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Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response.
Fribley AM, Cruz PG, Miller JR, Callaghan MU, Cai P, Narula N, Neubig RR, Showalter HD, Larsen SD, Kirchhoff PD, Larsen MJ, Burr DA, Schultz PJ, Jacobs RR, Tamayo-Castillo G, Ron D, Sherman DH, Kaufman RJ. Fribley AM, et al. Among authors: kirchhoff pd. J Biomol Screen. 2011 Sep;16(8):825-35. doi: 10.1177/1087057111414893. Epub 2011 Aug 15. J Biomol Screen. 2011. PMID: 21844328 Free PMC article.
Small molecule screening identifies regulators of the transcription factor ΔFosB.
Wang Y, Cesena TI, Ohnishi Y, Burger-Caplan R, Lam V, Kirchhoff PD, Larsen SD, Larsen MJ, Nestler EJ, Rudenko G. Wang Y, et al. Among authors: kirchhoff pd. ACS Chem Neurosci. 2012 Jul 18;3(7):546-56. doi: 10.1021/cn3000235. Epub 2012 Mar 29. ACS Chem Neurosci. 2012. PMID: 22860224 Free PMC article.
Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.
Waldschmidt HV, Homan KT, Cruz-Rodríguez O, Cato MC, Waninger-Saroni J, Larimore KM, Cannavo A, Song J, Cheung JY, Kirchhoff PD, Koch WJ, Tesmer JJ, Larsen SD. Waldschmidt HV, et al. Among authors: kirchhoff pd. J Med Chem. 2016 Apr 28;59(8):3793-807. doi: 10.1021/acs.jmedchem.5b02000. Epub 2016 Apr 13. J Med Chem. 2016. PMID: 27050625 Free PMC article.
Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence.
Zheng H, Colvin CJ, Johnson BK, Kirchhoff PD, Wilson M, Jorgensen-Muga K, Larsen SD, Abramovitch RB. Zheng H, et al. Among authors: kirchhoff pd. Nat Chem Biol. 2017 Feb;13(2):218-225. doi: 10.1038/nchembio.2259. Epub 2016 Dec 19. Nat Chem Biol. 2017. PMID: 27992879
30 results