Stiborová M - Search Results

1

Enzymes metabolizing aristolochic acid and their contribution to the development of aristolochic acid nephropathy and urothelial cancer.

Stiborová M, Martínek V, Frei E, Arlt VM, Schmeiser HH. Stiborová M, et al. Curr Drug Metab. 2013 Jul;14(6):695-705. doi: 10.2174/1389200211314060006. Curr Drug Metab. 2013. PMID: 23701164 Review.

2

Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.

Stiborová M, Frei E, Sopko B, Sopková K, Marková V, Lanková M, Kumstýrová T, Wiessler M, Schmeiser HH. Stiborová M, et al. Carcinogenesis. 2003 Oct;24(10):1695-703. doi: 10.1093/carcin/bgg119. Epub 2003 Jul 17. Carcinogenesis. 2003. PMID: 12869422

3

Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

Stiborová M, Frei E, Hodek P, Wiessler M, Schmeiser HH. Stiborová M, et al. Int J Cancer. 2005 Jan 10;113(2):189-97. doi: 10.1002/ijc.20564. Int J Cancer. 2005. PMID: 15386410 Free article.

4

The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen.

Stiborová M, Sopko B, Hodek P, Frei E, Schmeiser HH, Hudecek J. Stiborová M, et al. Cancer Lett. 2005 Nov 18;229(2):193-204. doi: 10.1016/j.canlet.2005.06.038. Epub 2005 Aug 24. Cancer Lett. 2005. PMID: 16125300

5

The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quinone oxidoreductase.

Stiborová M, Dracínská H, Hájková J, Kaderábková P, Frei E, Schmeiser HH, Soucek P, Phillips DH, Arlt VM. Stiborová M, et al. Drug Metab Dispos. 2006 Aug;34(8):1398-405. doi: 10.1124/dmd.106.009373. Epub 2006 May 19. Drug Metab Dispos. 2006. PMID: 16714372

6

Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy.

Stiborová M, Frei E, Arlt VM, Schmeiser HH. Stiborová M, et al. Mutat Res. 2008 Jan-Feb;658(1-2):55-67. doi: 10.1016/j.mrrev.2007.07.003. Epub 2007 Aug 6. Mutat Res. 2008. PMID: 17851120 Free article. Review.

7

Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid.

Sistkova J, Hudecek J, Hodek P, Frei E, Schmeiser HH, Stiborova M. Sistkova J, et al. Among authors: stiborova m. Neuro Endocrinol Lett. 2008 Oct;29(5):733-7. Neuro Endocrinol Lett. 2008. PMID: 18987598

8

The role of biotransformation enzymes in the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions and difficult answers.

Stiborova M, Frei E, Arlt VM, Schmeiser HH. Stiborova M, et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2009 Mar;153(1):5-11. doi: 10.5507/bp.2009.001. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2009. PMID: 19365519 Free article. Review.

9

Contribution of biotransformation enzymes to the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions, difficult answers.

Stiborová M, Hudeček J, Frei E, Schmeiser HH. Stiborová M, et al. Interdiscip Toxicol. 2008 Jun;1(1):8-12. doi: 10.2478/v10102-010-0023-1. Interdiscip Toxicol. 2008. PMID: 21218097 Free PMC article.

10

Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.

Levová K, Moserová M, Kotrbová V, Sulc M, Henderson CJ, Wolf CR, Phillips DH, Frei E, Schmeiser HH, Mares J, Arlt VM, Stiborová M. Levová K, et al. Among authors: stiborova m. Toxicol Sci. 2011 May;121(1):43-56. doi: 10.1093/toxsci/kfr050. Epub 2011 Feb 28. Toxicol Sci. 2011. PMID: 21362632 Free article.

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