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Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv.
Romano M, D'Souza S, Adnet PY, Laali R, Jurion F, Palfliet K, Huygen K. Romano M, et al. Among authors: huygen k. Vaccine. 2006 Apr 12;24(16):3353-64. doi: 10.1016/j.vaccine.2005.12.066. Epub 2006 Feb 6. Vaccine. 2006. PMID: 16488518
Increased pulmonary tumor necrosis factor alpha, interleukin-6 (IL-6), and IL-17A responses compensate for decreased gamma interferon production in anti-IL-12 autovaccine-treated, Mycobacterium bovis BCG-vaccinated mice.
Freches D, Romano M, Korf H, Renauld JC, Van Snick J, Uyttenhove C, Huygen K. Freches D, et al. Among authors: huygen k. Clin Vaccine Immunol. 2011 Jan;18(1):95-104. doi: 10.1128/CVI.00352-10. Epub 2010 Nov 17. Clin Vaccine Immunol. 2011. PMID: 21084465 Free PMC article.
Vaccination with plasmid DNA encoding mycobacterial antigen 85A stimulates a CD4+ and CD8+ T-cell epitopic repertoire broader than that stimulated by Mycobacterium tuberculosis H37Rv infection.
Denis O, Tanghe A, Palfliet K, Jurion F, van den Berg TP, Vanonckelen A, Ooms J, Saman E, Ulmer JB, Content J, Huygen K. Denis O, et al. Among authors: huygen k. Infect Immun. 1998 Apr;66(4):1527-33. doi: 10.1128/IAI.66.4.1527-1533.1998. Infect Immun. 1998. PMID: 9529077 Free PMC article.
Vaccination of mice with plasmid DNA carrying the gene for the major secreted mycobacterial antigen 85A (Ag85A) from Mycobacterium tuberculosis is a powerful technique for generating robust specific Thl helper T-cell responses, CD8+-mediated cytotoxicity, and protection against M …
Vaccination of mice with plasmid DNA carrying the gene for the major secreted mycobacterial antigen 85A (Ag85A) from Mycobacterium tuberculo …
241 results