Barak L - Search Results

1

Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1.

Lu J, Chen M, Ren XR, Wang J, Lyerly HK, Barak L, Chen W. Lu J, et al. Among authors: barak l. PLoS One. 2013 May 3;8(5):e63353. doi: 10.1371/journal.pone.0063353. Print 2013. PLoS One. 2013. PMID: 23671675 Free PMC article.

2

Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4.

Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ. Chen W, et al. Science. 2003 Sep 5;301(5638):1391-4. doi: 10.1126/science.1082808. Science. 2003. PMID: 12958364

3

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2.

Chen W, Ren XR, Nelson CD, Barak LS, Chen JK, Beachy PA, de Sauvage F, Lefkowitz RJ. Chen W, et al. Science. 2004 Dec 24;306(5705):2257-60. doi: 10.1126/science.1104135. Science. 2004. PMID: 15618519

4

Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway.

Wilbanks AM, Fralish GB, Kirby ML, Barak LS, Li YX, Caron MG. Wilbanks AM, et al. Among authors: barak ls. Science. 2004 Dec 24;306(5705):2264-7. doi: 10.1126/science.1104193. Science. 2004. PMID: 15618520

5

Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase.

Philipp M, Fralish GB, Meloni AR, Chen W, MacInnes AW, Barak LS, Caron MG. Philipp M, et al. Mol Biol Cell. 2008 Dec;19(12):5478-89. doi: 10.1091/mbc.e08-05-0448. Epub 2008 Sep 24. Mol Biol Cell. 2008. PMID: 18815277 Free PMC article.

6

The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling.

Chen M, Wang J, Lu J, Bond MC, Ren XR, Lyerly HK, Barak LS, Chen W. Chen M, et al. Biochemistry. 2009 Nov 3;48(43):10267-74. doi: 10.1021/bi9009677. Biochemistry. 2009. PMID: 19772353 Free PMC article.

7

Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine.

Wang J, Lu J, Bond MC, Chen M, Ren XR, Lyerly HK, Barak LS, Chen W. Wang J, et al. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9323-8. doi: 10.1073/pnas.0910712107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439738 Free PMC article.

8

Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach.

Chen W, Chen M, Barak LS. Chen W, et al. Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G293-300. doi: 10.1152/ajpgi.00005.2010. Epub 2010 May 27. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 20508156 Free PMC article. Review.

9

Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity.

Zhao P, Sharir H, Kapur A, Cowan A, Geller EB, Adler MW, Seltzman HH, Reggio PH, Heynen-Genel S, Sauer M, Chung TD, Bai Y, Chen W, Caron MG, Barak LS, Abood ME. Zhao P, et al. Mol Pharmacol. 2010 Oct;78(4):560-8. doi: 10.1124/mol.110.066746. Epub 2010 Jul 22. Mol Pharmacol. 2010. PMID: 20826425 Free PMC article.

10

Glucocorticoid hedgehog agonists in neurogenesis.

Wang J, Barak LS, Mook RA Jr, Chen W. Wang J, et al. Vitam Horm. 2011;87:207-15. doi: 10.1016/B978-0-12-386015-6.00030-5. Vitam Horm. 2011. PMID: 22127244 Free PMC article. Review.

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