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Synthesis of site-specific antibody-drug conjugates using unnatural amino acids.
Axup JY, Bajjuri KM, Ritland M, Hutchins BM, Kim CH, Kazane SA, Halder R, Forsyth JS, Santidrian AF, Stafin K, Lu Y, Tran H, Seller AJ, Biroc SL, Szydlik A, Pinkstaff JK, Tian F, Sinha SC, Felding-Habermann B, Smider VV, Schultz PG. Axup JY, et al. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16101-6. doi: 10.1073/pnas.1211023109. Epub 2012 Sep 17. Proc Natl Acad Sci U S A. 2012. PMID: 22988081 Free PMC article.
Self-assembled antibody multimers through peptide nucleic acid conjugation.
Kazane SA, Axup JY, Kim CH, Ciobanu M, Wold ED, Barluenga S, Hutchins BA, Schultz PG, Winssinger N, Smider VV. Kazane SA, et al. Among authors: axup jy. J Am Chem Soc. 2013 Jan 9;135(1):340-6. doi: 10.1021/ja309505c. Epub 2012 Dec 21. J Am Chem Soc. 2013. PMID: 23210862 Free PMC article.
Bispecific small molecule-antibody conjugate targeting prostate cancer.
Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, Zhou Q, Dubrovska A, Biroc SL, Marsden R, Pinstaff J, Smider VV, Schultz PG. Kim CH, et al. Among authors: axup jy. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17796-801. doi: 10.1073/pnas.1316026110. Epub 2013 Oct 14. Proc Natl Acad Sci U S A. 2013. PMID: 24127589 Free PMC article.
Multiformat T-cell-engaging bispecific antibodies targeting human breast cancers.
Cao Y, Axup JY, Ma JS, Wang RE, Choi S, Tardif V, Lim RK, Pugh HM, Lawson BR, Welzel G, Kazane SA, Sun Y, Tian F, Srinagesh S, Javahishvili T, Schultz PG, Kim CH. Cao Y, et al. Among authors: axup jy. Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7022-7. doi: 10.1002/anie.201500799. Epub 2015 Apr 27. Angew Chem Int Ed Engl. 2015. PMID: 25919418 Free PMC article.
Recruiting cytotoxic T cells to folate-receptor-positive cancer cells.
Kularatne SA, Deshmukh V, Gymnopoulos M, Biroc SL, Xia J, Srinagesh S, Sun Y, Zou N, Shimazu M, Pinkstaff J, Ensari S, Knudsen N, Manibusan A, Axup J, Kim C, Smider V, Javahishvili T, Schultz PG. Kularatne SA, et al. Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12101-12104. doi: 10.1002/anie.201306866. Epub 2013 Sep 25. Angew Chem Int Ed Engl. 2013. PMID: 24573789 Free PMC article.
Fc-Small Molecule Antibody Mimetics.
Wold ED, Axup JY, Felding BH, Smider VV. Wold ED, et al. Among authors: axup jy. Bioconjug Chem. 2015 Dec 16;26(12):2311-4. doi: 10.1021/acs.bioconjchem.5b00530. Epub 2015 Nov 13. Bioconjug Chem. 2015. PMID: 26536496 Free PMC article.
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