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A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors.
Vicente-Dueñas C, Romero-Camarero I, González-Herrero I, Alonso-Escudero E, Abollo-Jiménez F, Jiang X, Gutierrez NC, Orfao A, Marín N, Villar LM, Criado MC, Pintado B, Flores T, Alonso-López D, De Las Rivas J, Jiménez R, Criado FJ, Cenador MB, Lossos IS, Cobaleda C, Sánchez-García I. Vicente-Dueñas C, et al. EMBO J. 2012 Sep 12;31(18):3704-17. doi: 10.1038/emboj.2012.227. Epub 2012 Aug 17. EMBO J. 2012. PMID: 22903061 Free PMC article.
Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation.
Romero-Camarero I, Jiang X, Natkunam Y, Lu X, Vicente-Dueñas C, Gonzalez-Herrero I, Flores T, Garcia JL, McNamara G, Kunder C, Zhao S, Segura V, Fontan L, Martínez-Climent JA, García-Criado FJ, Theis JD, Dogan A, Campos-Sánchez E, Green MR, Alizadeh AA, Cobaleda C, Sánchez-García I, Lossos IS. Romero-Camarero I, et al. Nat Commun. 2013;4:1338. doi: 10.1038/ncomms2334. Nat Commun. 2013. PMID: 23299888 Free PMC article.
Cancer development induced by graded expression of Snail in mice.
Pérez-Mancera PA, Pérez-Caro M, González-Herrero I, Flores T, Orfao A, de Herreros AG, Gutiérrez-Adán A, Pintado B, Sagrera A, Sánchez-Martín M, Sánchez-García I. Pérez-Mancera PA, et al. Hum Mol Genet. 2005 Nov 15;14(22):3449-61. doi: 10.1093/hmg/ddi373. Epub 2005 Oct 5. Hum Mol Genet. 2005. PMID: 16207734
Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.
Green MR, Vicente-Dueñas C, Romero-Camarero I, Long Liu C, Dai B, González-Herrero I, García-Ramírez I, Alonso-Escudero E, Iqbal J, Chan WC, Campos-Sanchez E, Orfao A, Pintado B, Flores T, Blanco O, Jiménez R, Martínez-Climent JA, Criado FJ, Cenador MB, Zhao S, Natkunam Y, Lossos IS, Majeti R, Melnick A, Cobaleda C, Alizadeh AA, Sánchez-García I. Green MR, et al. Nat Commun. 2014 Jun 2;5:3904. doi: 10.1038/ncomms4904. Nat Commun. 2014. PMID: 24887457 Free PMC article.
Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice.
Vicente-Dueñas C, Fontán L, Gonzalez-Herrero I, Romero-Camarero I, Segura V, Aznar MA, Alonso-Escudero E, Campos-Sanchez E, Ruiz-Roca L, Barajas-Diego M, Sagardoy A, Martinez-Ferrandis JI, Abollo-Jimenez F, Bertolo C, Peñuelas I, Garcia-Criado FJ, García-Cenador MB, Tousseyn T, Agirre X, Prosper F, Garcia-Bragado F, McPhail ED, Lossos IS, Du MQ, Flores T, Hernandez-Rivas JM, Gonzalez M, Salar A, Bellosillo B, Conde E, Siebert R, Sagaert X, Cobaleda C, Sanchez-Garcia I, Martinez-Climent JA. Vicente-Dueñas C, et al. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10534-9. doi: 10.1073/pnas.1204127109. Epub 2012 Jun 11. Proc Natl Acad Sci U S A. 2012. PMID: 22689981 Free PMC article.
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