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Archetypal Arg169Cys mutation in NOTCH3 does not drive the pathogenesis in cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy via a loss-of-function mechanism.
Cognat E, Baron-Menguy C, Domenga-Denier V, Cleophax S, Fouillade C, Monet-Leprêtre M, Dewerchin M, Joutel A. Cognat E, et al. Among authors: baron menguy c. Stroke. 2014 Mar;45(3):842-9. doi: 10.1161/STROKEAHA.113.003339. Epub 2014 Jan 14. Stroke. 2014. PMID: 24425116
Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice.
Capone C, Cognat E, Ghezali L, Baron-Menguy C, Aubin D, Mesnard L, Stöhr H, Domenga-Denier V, Nelson MT, Joutel A. Capone C, et al. Among authors: baron menguy c. Ann Neurol. 2016 Mar;79(3):387-403. doi: 10.1002/ana.24573. Epub 2016 Feb 10. Ann Neurol. 2016. PMID: 26648042 Free PMC article.
Notch3ECD immunotherapy improves cerebrovascular responses in CADASIL mice.
Ghezali L, Capone C, Baron-Menguy C, Ratelade J, Christensen S, Østergaard Pedersen L, Domenga-Denier V, Pedersen JT, Joutel A. Ghezali L, et al. Among authors: baron menguy c. Ann Neurol. 2018 Aug;84(2):246-259. doi: 10.1002/ana.25284. Epub 2018 Aug 25. Ann Neurol. 2018. PMID: 30014602
19 results