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Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.
McGeachie AB, Odell LR, Quan A, Daniel JA, Chau N, Hill TA, Gorgani NN, Keating DJ, Cousin MA, van Dam EM, Mariana A, Whiting A, Perera S, Novelle A, Young KA, Deane FM, Gilbert J, Sakoff JA, Chircop M, McCluskey A, Robinson PJ. McGeachie AB, et al. Among authors: van dam em. ACS Chem Biol. 2013 Jul 19;8(7):1507-18. doi: 10.1021/cb400137p. Epub 2013 May 30. ACS Chem Biol. 2013. PMID: 23642287
Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II.
Quan A, McGeachie AB, Keating DJ, van Dam EM, Rusak J, Chau N, Malladi CS, Chen C, McCluskey A, Cousin MA, Robinson PJ. Quan A, et al. Among authors: van dam em. Mol Pharmacol. 2007 Dec;72(6):1425-39. doi: 10.1124/mol.107.034207. Epub 2007 Aug 16. Mol Pharmacol. 2007. PMID: 17702890
Ral: mediator of membrane trafficking.
van Dam EM, Robinson PJ. van Dam EM, et al. Int J Biochem Cell Biol. 2006;38(11):1841-7. doi: 10.1016/j.biocel.2006.04.006. Epub 2006 May 9. Int J Biochem Cell Biol. 2006. PMID: 16781882 Review.
The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1).
Foot JS, Deodhar M, Turner CI, Yin P, van Dam EM, Silva DG, Olivieri A, Holt A, McDonald IA. Foot JS, et al. Among authors: van dam em. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3935-40. doi: 10.1016/j.bmcl.2012.04.111. Epub 2012 Apr 30. Bioorg Med Chem Lett. 2012. PMID: 22595173
24 results