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Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells.
Mulay V, Wood P, Manetsch M, Darabi M, Cairns R, Hoque M, Chan KC, Reverter M, Alvarez-Guaita A, Rye KA, Rentero C, Heeren J, Enrich C, Grewal T. Mulay V, et al. Among authors: cairns r. PLoS One. 2013 Apr 25;8(4):e62667. doi: 10.1371/journal.pone.0062667. Print 2013. PLoS One. 2013. PMID: 23634230 Free PMC article.
Annexin A6 is a scaffold for PKCα to promote EGFR inactivation.
Koese M, Rentero C, Kota BP, Hoque M, Cairns R, Wood P, Vilà de Muga S, Reverter M, Alvarez-Guaita A, Monastyrskaya K, Hughes WE, Swarbrick A, Tebar F, Daly RJ, Enrich C, Grewal T. Koese M, et al. Among authors: cairns r. Oncogene. 2013 Jun 6;32(23):2858-72. doi: 10.1038/onc.2012.303. Epub 2012 Jul 16. Oncogene. 2013. PMID: 22797061
Annexins and endosomal signaling.
Tebar F, Gelabert-Baldrich M, Hoque M, Cairns R, Rentero C, Pol A, Grewal T, Enrich C. Tebar F, et al. Among authors: cairns r. Methods Enzymol. 2014;535:55-74. doi: 10.1016/B978-0-12-397925-4.00004-3. Methods Enzymol. 2014. PMID: 24377917
Annexins - scaffolds modulating PKC localization and signaling.
Hoque M, Rentero C, Cairns R, Tebar F, Enrich C, Grewal T. Hoque M, et al. Among authors: cairns r. Cell Signal. 2014 Jun;26(6):1213-25. doi: 10.1016/j.cellsig.2014.02.012. Epub 2014 Feb 27. Cell Signal. 2014. PMID: 24582587 Review.
Cholesterol regulates Syntaxin 6 trafficking at trans-Golgi network endosomal boundaries.
Reverter M, Rentero C, Garcia-Melero A, Hoque M, Vilà de Muga S, Alvarez-Guaita A, Conway JR, Wood P, Cairns R, Lykopoulou L, Grinberg D, Vilageliu L, Bosch M, Heeren J, Blasi J, Timpson P, Pol A, Tebar F, Murray RZ, Grewal T, Enrich C. Reverter M, et al. Among authors: cairns r. Cell Rep. 2014 May 8;7(3):883-97. doi: 10.1016/j.celrep.2014.03.043. Epub 2014 Apr 17. Cell Rep. 2014. PMID: 24746815 Free article.
Evidence for annexin A6-dependent plasma membrane remodelling of lipid domains.
Alvarez-Guaita A, Vilà de Muga S, Owen DM, Williamson D, Magenau A, García-Melero A, Reverter M, Hoque M, Cairns R, Cornely R, Tebar F, Grewal T, Gaus K, Ayala-Sanmartín J, Enrich C, Rentero C. Alvarez-Guaita A, et al. Among authors: cairns r. Br J Pharmacol. 2015 Apr;172(7):1677-90. doi: 10.1111/bph.13022. Epub 2015 Jan 20. Br J Pharmacol. 2015. PMID: 25409976 Free PMC article.
Identification of dual PPARα/γ agonists and their effects on lipid metabolism.
Gao Q, Hanh J, Váradi L, Cairns R, Sjöström H, Liao VW, Wood P, Balaban S, Ong JA, Lin HY, Lai F, Hoy AJ, Grewal T, Groundwater PW, Hibbs DE. Gao Q, et al. Among authors: cairns r. Bioorg Med Chem. 2015 Dec 15;23(24):7676-84. doi: 10.1016/j.bmc.2015.11.013. Epub 2015 Nov 14. Bioorg Med Chem. 2015. PMID: 26616289
Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration.
Balaban S, Shearer RF, Lee LS, van Geldermalsen M, Schreuder M, Shtein HC, Cairns R, Thomas KC, Fazakerley DJ, Grewal T, Holst J, Saunders DN, Hoy AJ. Balaban S, et al. Among authors: cairns r. Cancer Metab. 2017 Jan 13;5:1. doi: 10.1186/s40170-016-0163-7. eCollection 2017. Cancer Metab. 2017. PMID: 28101337 Free PMC article.
Role of hepatic Annexin A6 in fatty acid-induced lipid droplet formation.
Cairns R, Alvarez-Guaita A, Martínez-Saludes I, Wason SJ, Hanh J, Nagarajan SR, Hosseini-Beheshti E, Monastyrskaya K, Hoy AJ, Buechler C, Enrich C, Rentero C, Grewal T. Cairns R, et al. Exp Cell Res. 2017 Sep 15;358(2):397-410. doi: 10.1016/j.yexcr.2017.07.015. Epub 2017 Jul 14. Exp Cell Res. 2017. PMID: 28712927
274 results