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Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Colotta V, Catarzi D, Varano F, Lenzi O, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Traini C, Pugliese AM, Pedata F, Morizzo E, Moro S. Colotta V, et al. Among authors: traini c. Bioorg Med Chem. 2008 Jun 1;16(11):6086-102. doi: 10.1016/j.bmc.2008.04.039. Epub 2008 Apr 24. Bioorg Med Chem. 2008. PMID: 18468446
Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a new scaffold to develop potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Colotta V, Lenzi O, Catarzi D, Varano F, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Pugliese AM, Traini C, Pedata F, Morizzo E, Moro S. Colotta V, et al. Among authors: traini c. J Med Chem. 2009 Apr 23;52(8):2407-19. doi: 10.1021/jm8014876. J Med Chem. 2009. PMID: 19301821
49 results