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Discovery, synthesis and in combo studies of a tetrazole analogue of clofibric acid as a potent hypoglycemic agent.
Navarrete-Vázquez G, Alaniz-Palacios A, Hidalgo-Figueroa S, González-Acevedo C, Ávila-Villarreal G, Estrada-Soto S, Webster SP, Medina-Franco JL, López-Vallejo F, Guerrero-Álvarez J, Tlahuext H. Navarrete-Vázquez G, et al. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3244-7. doi: 10.1016/j.bmcl.2013.03.122. Epub 2013 Apr 5. Bioorg Med Chem Lett. 2013. PMID: 23597793
A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition.
Torres-Piedra M, Ortiz-Andrade R, Villalobos-Molina R, Singh N, Medina-Franco JL, Webster SP, Binnie M, Navarrete-Vázquez G, Estrada-Soto S. Torres-Piedra M, et al. Eur J Med Chem. 2010 Jun;45(6):2606-12. doi: 10.1016/j.ejmech.2010.02.049. Epub 2010 Mar 1. Eur J Med Chem. 2010. PMID: 20346546
Design, synthesis, and docking of highly hypolipidemic agents: Schizosaccharomyces pombe as a new model for evaluating alpha-asarone-based HMG-CoA reductase inhibitors.
Argüelles N, Sánchez-Sandoval E, Mendieta A, Villa-Tanaca L, Garduño-Siciliano L, Jiménez F, Cruz Mdel C, Medina-Franco JL, Chamorro-Cevallos G, Tamariz J. Argüelles N, et al. Bioorg Med Chem. 2010 Jun 15;18(12):4238-48. doi: 10.1016/j.bmc.2010.04.096. Epub 2010 May 10. Bioorg Med Chem. 2010. PMID: 20576575
Visualization of molecular fingerprints.
Owen JR, Nabney IT, Medina-Franco JL, López-Vallejo F. Owen JR, et al. J Chem Inf Model. 2011 Jul 25;51(7):1552-63. doi: 10.1021/ci1004042. Epub 2011 Jul 8. J Chem Inf Model. 2011. PMID: 21696145
242 results