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Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example.
Liguori MJ, Ditewig AC, Maddox JF, Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Waring JF, Ganey PE, Roth RA, Blomme EA. Liguori MJ, et al. Among authors: blomme ea. Int J Mol Sci. 2010 Nov 18;11(11):4697-714. doi: 10.3390/ijms11114697. Int J Mol Sci. 2010. PMID: 21151465 Free PMC article.
AhR activation underlies the CYP1A autoinduction by A-998679 in rats.
Liguori MJ, Lee CH, Liu H, Ciurlionis R, Ditewig AC, Doktor S, Andracki ME, Gagne GD, Waring JF, Marsh KC, Gopalakrishnan M, Blomme EA, Yang Y. Liguori MJ, et al. Among authors: blomme ea. Front Genet. 2012 Oct 26;3:213. doi: 10.3389/fgene.2012.00213. eCollection 2012. Front Genet. 2012. PMID: 23112805 Free PMC article.
Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models.
Weaver RJ, Blomme EA, Chadwick AE, Copple IM, Gerets HHJ, Goldring CE, Guillouzo A, Hewitt PG, Ingelman-Sundberg M, Jensen KG, Juhila S, Klingmüller U, Labbe G, Liguori MJ, Lovatt CA, Morgan P, Naisbitt DJ, Pieters RHH, Snoeys J, van de Water B, Williams DP, Park BK. Weaver RJ, et al. Among authors: blomme ea. Nat Rev Drug Discov. 2020 Feb;19(2):131-148. doi: 10.1038/s41573-019-0048-x. Epub 2019 Nov 20. Nat Rev Drug Discov. 2020. PMID: 31748707 Free article. Review.
88 results