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The binding sites of microtubule-stabilizing agents.
Field JJ, Díaz JF, Miller JH. Field JJ, et al. Among authors: diaz jf. Chem Biol. 2013 Mar 21;20(3):301-15. doi: 10.1016/j.chembiol.2013.01.014. Chem Biol. 2013. PMID: 23521789 Review.
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
Buey RM, Calvo E, Barasoain I, Pineda O, Edler MC, Matesanz R, Cerezo G, Vanderwal CD, Day BW, Sorensen EJ, López JA, Andreu JM, Hamel E, Díaz JF. Buey RM, et al. Among authors: diaz jf. Nat Chem Biol. 2007 Feb;3(2):117-25. doi: 10.1038/nchembio853. Epub 2007 Jan 7. Nat Chem Biol. 2007. PMID: 17206139 Free article.
Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.
Canales A, Rodríguez-Salarichs J, Trigili C, Nieto L, Coderch C, Andreu JM, Paterson I, Jiménez-Barbero J, Díaz JF. Canales A, et al. Among authors: diaz jf. ACS Chem Biol. 2011 Aug 19;6(8):789-99. doi: 10.1021/cb200099u. Epub 2011 May 13. ACS Chem Biol. 2011. PMID: 21539341 Free article.
Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
Field JJ, Pera B, Calvo E, Canales A, Zurwerra D, Trigili C, Rodríguez-Salarichs J, Matesanz R, Kanakkanthara A, Wakefield SJ, Singh AJ, Jiménez-Barbero J, Northcote P, Miller JH, López JA, Hamel E, Barasoain I, Altmann KH, Díaz JF. Field JJ, et al. Among authors: diaz jf. Chem Biol. 2012 Jun 22;19(6):686-98. doi: 10.1016/j.chembiol.2012.05.008. Chem Biol. 2012. PMID: 22726683 Free PMC article.
211 results