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Conjugation of a Ru(II) arene complex to neomycin or to guanidinoneomycin leads to compounds with differential cytotoxicities and accumulation between cancer and normal cells.
Mol Pharm. 2013 May 6;10(5):1964-76. doi: 10.1021/mp300723b. Epub 2013 Apr 5.
Mol Pharm. 2013.
PMID: 23510087
Free article.
Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium(II) complex.
Barragán F, López-Senín P, Salassa L, Betanzos-Lara S, Habtemariam A, Moreno V, Sadler PJ, Marchán V.
Barragán F, et al. Among authors: lopez senin p.
J Am Chem Soc. 2011 Sep 7;133(35):14098-108. doi: 10.1021/ja205235m. Epub 2011 Aug 11.
J Am Chem Soc. 2011.
PMID: 21797210
Free article.
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Exploring the effect of aminoglycoside guanidinylation on ligands for Tau exon 10 splicing regulatory element RNA.
López-Senín P, Artigas G, Marchán V.
López-Senín P, et al.
Org Biomol Chem. 2012 Dec 14;10(46):9243-54. doi: 10.1039/c2ob26623g. Epub 2012 Oct 29.
Org Biomol Chem. 2012.
PMID: 23108673
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Ametantrone-based compounds as potential regulators of Tau pre-mRNA alternative splicing.
Artigas G, López-Senín P, González C, Escaja N, Marchán V.
Artigas G, et al. Among authors: lopez senin p.
Org Biomol Chem. 2015 Jan 14;13(2):452-64. doi: 10.1039/c4ob01925c. Epub 2014 Nov 5.
Org Biomol Chem. 2015.
PMID: 25372055
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Identification of ligands for the Tau exon 10 splicing regulatory element RNA by using dynamic combinatorial chemistry.
López-Senín P, Gómez-Pinto I, Grandas A, Marchán V.
López-Senín P, et al.
Chemistry. 2011 Feb 7;17(6):1946-53. doi: 10.1002/chem.201002065. Epub 2011 Jan 5.
Chemistry. 2011.
PMID: 21274946
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