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RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activity.
Druker J, Liberman AC, Antunica-Noguerol M, Gerez J, Paez-Pereda M, Rein T, Iñiguez-Lluhí JA, Holsboer F, Arzt E. Druker J, et al. Among authors: antunica noguerol m. Mol Cell Biol. 2013 Jun;33(11):2116-27. doi: 10.1128/MCB.01470-12. Epub 2013 Mar 18. Mol Cell Biol. 2013. PMID: 23508108 Free PMC article.
Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells.
Liberman AC, Antunica-Noguerol M, Ferraz-de-Paula V, Palermo-Neto J, Castro CN, Druker J, Holsboer F, Perone MJ, Gerlo S, De Bosscher K, Haegeman G, Arzt E. Liberman AC, et al. Among authors: antunica noguerol m. PLoS One. 2012;7(4):e35155. doi: 10.1371/journal.pone.0035155. Epub 2012 Apr 9. PLoS One. 2012. PMID: 22496903 Free PMC article.
GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A.
Barcala Tabarrozzi AE, Andreone L, Deckers J, Castro CN, Gimeno ML, Ariolfo L, Berguer PM, Antunica-Noguerol M, Liberman AC, Vettorazzi S, Tuckermann JP, De Bosscher K, Perone MJ. Barcala Tabarrozzi AE, et al. Among authors: antunica noguerol m. Sci Rep. 2016 Nov 18;6:36646. doi: 10.1038/srep36646. Sci Rep. 2016. PMID: 27857212 Free PMC article.