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Ursodeoxycholic acid attenuates colonic epithelial secretory function.
Kelly OB, Mroz MS, Ward JB, Colliva C, Scharl M, Pellicciari R, Gilmer JF, Fallon PG, Hofmann AF, Roda A, Murray FE, Keely SJ. Kelly OB, et al. Among authors: fallon pg. J Physiol. 2013 May 1;591(9):2307-18. doi: 10.1113/jphysiol.2013.252544. Epub 2013 Mar 18. J Physiol. 2013. PMID: 23507881 Free PMC article.
Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier.
Bowie RV, Donatello S, Lyes C, Owens MB, Babina IS, Hudson L, Walsh SV, O'Donoghue DP, Amu S, Barry SP, Fallon PG, Hopkins AM. Bowie RV, et al. Among authors: fallon pg. Am J Physiol Gastrointest Liver Physiol. 2012 Apr 15;302(8):G781-93. doi: 10.1152/ajpgi.00002.2011. Epub 2012 Jan 12. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22241861 Free article.
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
Tambuwala MM, Cummins EP, Lenihan CR, Kiss J, Stauch M, Scholz CC, Fraisl P, Lasitschka F, Mollenhauer M, Saunders SP, Maxwell PH, Carmeliet P, Fallon PG, Schneider M, Taylor CT. Tambuwala MM, et al. Among authors: fallon pg. Gastroenterology. 2010 Dec;139(6):2093-101. doi: 10.1053/j.gastro.2010.06.068. Epub 2010 Jun 30. Gastroenterology. 2010. PMID: 20600011
Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.
Spence S, Greene MK, Fay F, Hams E, Saunders SP, Hamid U, Fitzgerald M, Beck J, Bains BK, Smyth P, Themistou E, Small DM, Schmid D, O'Kane CM, Fitzgerald DC, Abdelghany SM, Johnston JA, Fallon PG, Burrows JF, McAuley DF, Kissenpfennig A, Scott CJ. Spence S, et al. Among authors: fallon pg. Sci Transl Med. 2015 Sep 2;7(303):303ra140. doi: 10.1126/scitranslmed.aab3459. Sci Transl Med. 2015. PMID: 26333936
297 results