Chalmers DK - Search Results

1

(+)-Fluorenylethylchloroformate (FLEC)--improved synthesis for application in chiral analysis and peptidomimetic synthesis.

Camerino MA, Chalmers DK, Thompson PE. Camerino MA, et al. Among authors: chalmers dk. Org Biomol Chem. 2013 Apr 28;11(16):2571-3. doi: 10.1039/c3ob40218e. Org Biomol Chem. 2013. PMID: 23483118

2

Thiazolidinedione-based PI3Kα inhibitors: an analysis of biochemical and virtual screening methods.

Pinson JA, Schmidt-Kittler O, Zhu J, Jennings IG, Kinzler KW, Vogelstein B, Chalmers DK, Thompson PE. Pinson JA, et al. Among authors: chalmers dk. ChemMedChem. 2011 Mar 7;6(3):514-22. doi: 10.1002/cmdc.201000467. Epub 2011 Jan 4. ChemMedChem. 2011. PMID: 21360822 Free PMC article.

3

L-Aminoacyl-triazine derivatives are isoform-selective PI3Kβ inhibitors that target non-conserved Asp862 of PI3Kβ.

Pinson JA, Zheng Z, Miller MS, Chalmers DK, Jennings IG, Thompson PE. Pinson JA, et al. Among authors: chalmers dk. ACS Med Chem Lett. 2013 Feb 14;4(2):206-210. doi: 10.1021/ml300336j. ACS Med Chem Lett. 2013. PMID: 23795239 Free PMC article.

4

Synthesis and Pharmacological Evaluation of 4-Iminothiazolidinones for Inhibition of PI3 Kinase.

Pinson JA, Schmidt-Kittler O, Frazzetto M, Zheng Z, Jennings IG, Kinzler KW, Vogelstein B, Chalmers DK, Thompson PE. Pinson JA, et al. Among authors: chalmers dk. Aust J Chem. 2012 Jan 10;65(10):1396-1404. doi: 10.1071/CH12140. Aust J Chem. 2012. PMID: 23997244 Free PMC article.

5

A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent.

Yap BK, Leung EW, Yagi H, Galea CA, Chhabra S, Chalmers DK, Nicholson SE, Thompson PE, Norton RS. Yap BK, et al. Among authors: chalmers dk. J Med Chem. 2014 Aug 28;57(16):7006-15. doi: 10.1021/jm500596j. Epub 2014 Aug 6. J Med Chem. 2014. PMID: 25068993

6

Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction.

Yap BK, Harjani JR, Leung EW, Nicholson SE, Scanlon MJ, Chalmers DK, Thompson PE, Baell JB, Norton RS. Yap BK, et al. Among authors: chalmers dk. FEBS Lett. 2016 Mar;590(6):696-704. doi: 10.1002/1873-3468.12115. Epub 2016 Mar 6. FEBS Lett. 2016. PMID: 26921848 Free article.

7

Design, Synthesis, and Characterization of Cyclic Peptidomimetics of the Inducible Nitric Oxide Synthase Binding Epitope That Disrupt the Protein-Protein Interaction Involving SPRY Domain-Containing Suppressor of Cytokine Signaling Box Protein (SPSB) 2 and Inducible Nitric Oxide Synthase.

Harjani JR, Yap BK, Leung EW, Lucke A, Nicholson SE, Scanlon MJ, Chalmers DK, Thompson PE, Norton RS, Baell JB. Harjani JR, et al. Among authors: chalmers dk. J Med Chem. 2016 Jun 23;59(12):5799-809. doi: 10.1021/acs.jmedchem.6b00386. Epub 2016 Jun 8. J Med Chem. 2016. PMID: 27214043

8

Beta amino acid-modified and fluorescently labelled kisspeptin analogues with potent KISS1R activity.

Camerino MA, Liu M, Moriya S, Kitahashi T, Mahgoub A, Mountford SJ, Chalmers DK, Soga T, Parhar IS, Thompson PE. Camerino MA, et al. Among authors: chalmers dk. J Pept Sci. 2016 Jun;22(6):406-14. doi: 10.1002/psc.2883. J Pept Sci. 2016. PMID: 27282137

9

Structure-Activity Studies of β-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.

Wang G, Drinkwater N, Drew DR, MacRaild CA, Chalmers DK, Mohanty B, Lim SS, Anders RF, Beeson JG, Thompson PE, McGowan S, Simpson JS, Norton RS, Scanlon MJ. Wang G, et al. Among authors: chalmers dk. J Mol Biol. 2016 Oct 9;428(20):3986-3998. doi: 10.1016/j.jmb.2016.07.001. Epub 2016 Jul 14. J Mol Biol. 2016. PMID: 27422009

10

Parallel and antiparallel cyclic d/l peptide nanotubes.

Silk MR, Newman J, Ratcliffe JC, White JF, Caradoc-Davies T, Price JR, Perrier S, Thompson PE, Chalmers DK. Silk MR, et al. Among authors: chalmers dk. Chem Commun (Camb). 2017 Jun 21;53(49):6613-6616. doi: 10.1039/c7cc00846e. Epub 2017 Jun 5. Chem Commun (Camb). 2017. PMID: 28581562

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