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Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains.
Forst AH, Karlberg T, Herzog N, Thorsell AG, Gross A, Feijs KL, Verheugd P, Kursula P, Nijmeijer B, Kremmer E, Kleine H, Ladurner AG, Schüler H, Lüscher B. Forst AH, et al. Among authors: ladurner ag. Structure. 2013 Mar 5;21(3):462-75. doi: 10.1016/j.str.2012.12.019. Structure. 2013. PMID: 23473667 Free article.
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation.
Timinszky G, Till S, Hassa PO, Hothorn M, Kustatscher G, Nijmeijer B, Colombelli J, Altmeyer M, Stelzer EH, Scheffzek K, Hottiger MO, Ladurner AG. Timinszky G, et al. Among authors: ladurner ag. Nat Struct Mol Biol. 2009 Sep;16(9):923-9. doi: 10.1038/nsmb.1664. Epub 2009 Aug 13. Nat Struct Mol Biol. 2009. PMID: 19680243
ADP-ribosyltransferases, an update on function and nomenclature.
Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagné JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehtiö L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawłowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Yélamos J, Yu X, Zaja R, Ziegler M. Lüscher B, et al. FEBS J. 2022 Dec;289(23):7399-7410. doi: 10.1111/febs.16142. Epub 2021 Sep 13. FEBS J. 2022. PMID: 34323016 Free PMC article.
PARG: a macrodomain in disguise.
Hassler M, Jankevicius G, Ladurner AG. Hassler M, et al. Among authors: ladurner ag. Structure. 2011 Oct 12;19(10):1351-3. doi: 10.1016/j.str.2011.09.007. Structure. 2011. PMID: 22000507 Free article.
The macro domain is an ADP-ribose binding module.
Karras GI, Kustatscher G, Buhecha HR, Allen MD, Pugieux C, Sait F, Bycroft M, Ladurner AG. Karras GI, et al. Among authors: ladurner ag. EMBO J. 2005 Jun 1;24(11):1911-20. doi: 10.1038/sj.emboj.7600664. Epub 2005 May 19. EMBO J. 2005. PMID: 15902274 Free PMC article.
A family of macrodomain proteins reverses cellular mono-ADP-ribosylation.
Jankevicius G, Hassler M, Golia B, Rybin V, Zacharias M, Timinszky G, Ladurner AG. Jankevicius G, et al. Among authors: ladurner ag. Nat Struct Mol Biol. 2013 Apr;20(4):508-14. doi: 10.1038/nsmb.2523. Epub 2013 Mar 10. Nat Struct Mol Biol. 2013. PMID: 23474712 Free PMC article.
MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.
Kozlowski M, Corujo D, Hothorn M, Guberovic I, Mandemaker IK, Blessing C, Sporn J, Gutierrez-Triana A, Smith R, Portmann T, Treier M, Scheffzek K, Huet S, Timinszky G, Buschbeck M, Ladurner AG. Kozlowski M, et al. Among authors: ladurner ag. EMBO Rep. 2018 Oct;19(10):e44445. doi: 10.15252/embr.201744445. Epub 2018 Sep 3. EMBO Rep. 2018. PMID: 30177554 Free PMC article.
A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene.
Singh HR, Nardozza AP, Möller IR, Knobloch G, Kistemaker HAV, Hassler M, Harrer N, Blessing C, Eustermann S, Kotthoff C, Huet S, Mueller-Planitz F, Filippov DV, Timinszky G, Rand KD, Ladurner AG. Singh HR, et al. Among authors: ladurner ag. Mol Cell. 2017 Dec 7;68(5):860-871.e7. doi: 10.1016/j.molcel.2017.11.019. Mol Cell. 2017. PMID: 29220653 Free article.
99 results